PDF(Pubmed)
Abstract：
UNASSIGNED: Childhood Cancer Survivors (CCSs) are more likely to report sexual dysfunction than people without cancer history. Sexual functioning encompasses more than just sexual dysfunction. The scarcity of information regarding the status and influencing factors of sexual functioning in CCSs, hampers to devise suitable screening or interventions. This review aims to summarize research progress on sexual functioning and associated factors among CCSs.
UNASSIGNED: This review protocol is registered in PROSPERO(CRD42023427939) and performed according to PRISMA guidelines. From inception to November 15, 2023, a comprehensive search was conducted in PubMed, EMBASE, CINAHL, Web of Science, SCOPUS, PsycINFO, CNKI Database, Wanfang of Chinese Database, SinoMed Database and Cochrane Library on sexual functioning and childhood cancer survivors. Inclusion criteria were English or Chinese studies focusing on sexual functioning and related factors of cancer survivors, who diagnosed with cancer before 18 years old, and were adult and disease-free when participating in the study. Studies were excluded if the focus was on adult cancer patients or without age information.
UNASSIGNED: 395 records were retrieved, and 22 studies were finally included in this review. Results suggest that CCSs experience a substantial burden of sexual issues, including delayed psychosexual development, low satisfaction, and high prevalence of dysfunction. Underlying factors related to sexual functioning of CCSs were identified, including demographic, cancer treatment-related, psychological, and physiological factors. The historical change in research on sexual functioning was summarized.
UNASSIGNED: Research on sexual functioning among CCSs is limited. The extent to which cancer and related treatments affect sexual functioning remains largely unknown. The relationships between various factors and mechanisms underlying sexual functioning need to be confirmed by more rigorous studies to enable effective interventions to be developed.
UNASSIGNED: None.
UNASSIGNED: This review protocol is registered in PROSPERO(CRD42023427939) and performed according to PRISMA guidelines. From inception to November 15, 2023, a comprehensive search was conducted in PubMed, EMBASE, CINAHL, Web of Science, SCOPUS, PsycINFO, CNKI Database, Wanfang of Chinese Database, SinoMed Database and Cochrane Library on sexual functioning and childhood cancer survivors. Inclusion criteria were English or Chinese studies focusing on sexual functioning and related factors of cancer survivors, who diagnosed with cancer before 18 years old, and were adult and disease-free when participating in the study. Studies were excluded if the focus was on adult cancer patients or without age information.
UNASSIGNED: 395 records were retrieved, and 22 studies were finally included in this review. Results suggest that CCSs experience a substantial burden of sexual issues, including delayed psychosexual development, low satisfaction, and high prevalence of dysfunction. Underlying factors related to sexual functioning of CCSs were identified, including demographic, cancer treatment-related, psychological, and physiological factors. The historical change in research on sexual functioning was summarized.
UNASSIGNED: Research on sexual functioning among CCSs is limited. The extent to which cancer and related treatments affect sexual functioning remains largely unknown. The relationships between various factors and mechanisms underlying sexual functioning need to be confirmed by more rigorous studies to enable effective interventions to be developed.
UNASSIGNED: None.
摘要：
■儿童癌症幸存者（CCS）比没有癌症史的人更有可能报告性功能障碍。性功能不仅包括性功能障碍。有关CCS性功能状况和影响因素的信息匮乏，阻碍设计合适的筛查或干预措施。本文旨在总结CCS中性功能及相关因素的研究进展。
■此审查方案在PROSPERO（CRD42023427939）中注册，并根据PRISMA指南执行。从成立到2023年11月15日，在PubMed进行了全面搜索，EMBASE,CINAHL,WebofScience,Scopus,PsycINFO,CNKI数据库,万方中国数据库,SinoMed数据库和Cochrane图书馆关于性功能和儿童癌症幸存者。纳入标准是针对癌症幸存者性功能和相关因素的英文或中文研究，在18岁之前被诊断出患有癌症，并且在参与研究时是成年人和无病。如果重点是成人癌症患者或没有年龄信息，则排除研究。
■检索了395条记录，22项研究最终纳入本综述.结果表明，CCS经历了大量的性问题负担，包括性心理发育延迟,满意度低,和高患病率的功能障碍。确定了与CCS性功能相关的潜在因素，包括人口统计，癌症治疗相关，心理,和生理因素。总结了性功能研究的历史变迁。
■关于CCS中性功能的研究有限。癌症和相关治疗对性功能的影响程度仍在很大程度上未知。需要通过更严格的研究来确认各种因素与性功能机制之间的关系，以开发有效的干预措施。
■无。
■此审查方案在PROSPERO（CRD42023427939）中注册，并根据PRISMA指南执行。从成立到2023年11月15日，在PubMed进行了全面搜索，EMBASE,CINAHL,WebofScience,Scopus,PsycINFO,CNKI数据库,万方中国数据库,SinoMed数据库和Cochrane图书馆关于性功能和儿童癌症幸存者。纳入标准是针对癌症幸存者性功能和相关因素的英文或中文研究，在18岁之前被诊断出患有癌症，并且在参与研究时是成年人和无病。如果重点是成人癌症患者或没有年龄信息，则排除研究。
■检索了395条记录，22项研究最终纳入本综述.结果表明，CCS经历了大量的性问题负担，包括性心理发育延迟,满意度低,和高患病率的功能障碍。确定了与CCS性功能相关的潜在因素，包括人口统计，癌症治疗相关，心理,和生理因素。总结了性功能研究的历史变迁。
■关于CCS中性功能的研究有限。癌症和相关治疗对性功能的影响程度仍在很大程度上未知。需要通过更严格的研究来确认各种因素与性功能机制之间的关系，以开发有效的干预措施。
■无。
