Abstract：
A 50-year-old man with a triglyceride (TG) level of 11,397 mg/dL was admitted to our hospital. He consumed a high-fat and high-carbohydrate diet as well as more than 100 g of alcohol per day. He had type 2 diabetes and obesity and had previously suffered from severe acute pancreatitis twice. A genetic analysis revealed compound heterozygous mutations in APOA5 (c.56C>G and c.553G>T). In addition to low-fat meals and alcohol cessation, administration of pemafibrate lowered his triglyceride levels to <150 mg/dL.
摘要：
我们医院收治了一名50岁的甘油三酸酯（TG）水平为11,397mg/dL的男性。他每天摄入高脂肪和高碳水化合物的饮食以及超过100克的酒精。他患有2型糖尿病和肥胖症，以前曾两次患有严重的急性胰腺炎。遗传分析显示APOA5中的复合杂合突变(c.56C>G和c.553G>T)。除了低脂膳食和戒酒，服用培马贝特将他的甘油三酯水平降低至<150mg/dL。
