关键词: additive manufacturing antibacterial bactericide biomedical direct ink writing membranes

Mesh : Anti-Bacterial Agents / pharmacology chemistry Ink Biocompatible Materials / chemistry Membranes, Artificial Humans Printing, Three-Dimensional Materials Testing Prostheses and Implants Animals Writing Bacteria

来  源:   DOI:10.1088/1748-605X/ad66a4

Abstract:
The necessity for orthopedic prostheses, implants, and membranes to treat diseases, trauma, and other disasters has increased as the risk of survive through various factors has intensified exponentially. Considering exponential growth in demand, it has been observed that the traditional technology of grafts and membranes lags to fulfill the demand and effectiveness simultaneously. These challenges in traditional methodologies prompted a revolutionary shift in the biomedical industry when additive manufacturing (AM) emerged as an alternative fabrication technique for medical equipments such as prostheses, implants, and membranes. However these techniques were fast and precise the major attributes of the biomedical materials were the processability, bactericidal nature, biocompatibility, biodegradability, and nontoxicity together with good mechanical properties. Major challenges faced by researchers in the present-day scenario regarding materials are the lack of bactericidal attributes in tailored material, though having better mechanical as well as biocompatible properties, which, on the other hand, are primary critical factors too, in the healthcare sector. Hence considering the advantages of AM and need for membranes with bacteriacidal attributes this present review will highlight the studies based on the manufacturing of membranes with bacteria-resistant properties majorly using direct ink writing and some AM techniques and the reasoning behind the antibacterial attributes of those composite materials.
摘要:
矫形假体的必要性,植入物,和膜来治疗疾病,创伤,由于各种因素的生存风险呈指数级加剧,其他灾害也有所增加。考虑到需求的指数增长,已经观察到,传统的移植物和膜技术滞后于同时满足需求和有效性。传统方法中的这些挑战促使生物医学行业发生了革命性的转变,当增材制造(AM)成为假肢等医疗设备的替代制造技术时,植入物,和膜。然而,这些技术是快速和精确的生物医学材料的主要属性是可加工性,杀菌性质,生物相容性,生物降解性,无毒性和良好的机械性能。研究人员在当今的材料场景中面临的主要挑战是在定制材料中缺乏杀菌属性,虽然具有更好的机械和生物相容性,which,另一方面,也是主要的关键因素,在医疗保健领域。因此,考虑到增材制造的优势和对具有杀菌属性的膜的需求,本综述将重点介绍基于主要使用直接墨水书写和一些增材制造技术制造具有细菌抗性的膜的研究,以及这些复合材料的抗菌属性背后的推理。
公众号