Abstract:
Viruses, causal agents of devastating diseases in plants, are obligate intracellular pathogens composed of a nucleic acid genome and a limited number of viral proteins. The diversity of plant viruses, their diminutive molecular nature, and their symplastic localization pose challenges to understanding the interplay between these pathogens and their hosts in the currently accepted framework of plant innate immunity. It is clear, nevertheless, that plants can recognize the presence of a virus and activate antiviral immune responses, although our knowledge of the breadth of invasion signals and the underpinning sensing events is far from complete. Below, I discuss some of the demonstrated or hypothesized mechanisms enabling viral recognition in plants, the step preceding the onset of antiviral immunity, as well as the strategies viruses have evolved to evade or suppress their detection.
摘要:
病毒,植物中毁灭性疾病的病原体,是由核酸基因组和有限数量的病毒蛋白组成的专性细胞内病原体。植物病毒的多样性,它们的小分子性质,它们的共生定位对理解这些病原体和它们的宿主之间在目前公认的植物先天免疫框架中的相互作用提出了挑战。很清楚,然而,植物可以识别病毒的存在并激活抗病毒免疫反应,尽管我们对入侵信号的广度和基础感知事件的了解还远远不够。下面,我讨论了一些证明或假设的能够在植物中识别病毒的机制,抗病毒免疫开始前的步骤,以及策略病毒已经进化到逃避或抑制它们的检测。