Abstract：
Increasing the number of teats in sheep helps to improve the survival rate of sheep lambs after birth. In order to analyze the candidate genes related to the formation of multiple teats in Hu sheep, the present study was conducted to investigate the genetic pattern of multiple teats in Hu sheep. In this study, based on genome-wide data from 157 Hu sheep, Fst, xp-EHH, Pi and iHS signaling were performed, and the top 5% signal regions of each analyzed result were annotated based on the Oar_v4.0 for sheep. The results show that a total of 142 SNP loci were selected. We found that PTPRG, TMEM117 and LRP1B genes were closely associated with polypodium formation in Hu sheep, in addition, among the candidate genes related to polypodium we found genes such as TMEM117, SLC25A21 and NCKAP5 related to milk traits. The present study screened out candidate genes for the formation of multiple teats at the genomic level in Hu sheep.
摘要：
增加绵羊的乳头数量有助于提高绵羊出生后的成活率。为了分析湖羊多个乳头形成的相关候选基因,本研究旨在研究湖羊多个乳头的遗传模式。在这项研究中,基于157只湖羊的全基因组数据，Fst,xp-EHH,进行Pi和iHS信号传导，并基于绵羊的Oar_v4.0注释了每个分析结果的前5%信号区域。结果表明,共筛选出142个SNP位点。我们发现PTPRG,TMEM117和LRP1B基因与湖羊息肉形成密切相关，此外,在与息肉相关的候选基因中，我们发现了与牛奶性状相关的基因，例如TMEM117，SLC25A21和NCKAP5。本研究在基因组水平上筛选出了湖羊多个乳头形成的候选基因。
