Abstract：
OBJECTIVE: To investigate the trimester-specific associations between maternal total physical activity level vs moderate-to-vigorous exercise and fetal growth disorders.
METHODS: We analyzed 2062 mother-neonate pairs participating in the longitudinal China Medical University Birth Cohort Study. The Pregnancy Physical Activity Questionnaire was used to assess the physical activity level of women during the three trimesters. A higher level of total physical activity was defined as meeting or exceeding the cohort-specific 75th percentile, and a higher level of exercise was defined according to the Physical Activity Guidelines for Americans. Fetal growth disorder was defined as small-for-gestational age (SGA) or large-for-gestational age (LGA) at birth.
RESULTS: Of the neonates included in this study, 7.1% were SGA and 15.5% were LGA. A higher level of total physical activity during the first trimester (adjusted relative risk (aRR), 0.62 (95% CI, 0.42-0.91)) and second trimester (aRR, 0.62 (95% CI, 0.41-0.95)) was associated with a lower risk of SGA, and a higher level of total physical activity during the third trimester was associated with a lower risk of LGA (aRR, 0.73 (95% CI, 0.54-0.97)). When analyzing physical activity by subtype, a higher level of occupational physical activity during the first and second trimesters was associated negatively with SGA risk, and higher levels of occupational and low-intensity physical activity during the first trimester were associated negatively with LGA risk. No significant association was found between maternal adherence to the Physical Activity Guidelines for Americans and risk of fetal growth disorders.
CONCLUSIONS: A higher total physical activity level during the first and second trimesters was associated with a decreased risk of SGA, whereas a higher total physical activity level in the third trimester was associated with a decreased risk of LGA. Pregnant women should be advised to increase their total physical activity levels instead of focusing on engaging in only moderate-to-vigorous exercise. © 2024 International Society of Ultrasound in Obstetrics and Gynecology.
METHODS: We analyzed 2062 mother-neonate pairs participating in the longitudinal China Medical University Birth Cohort Study. The Pregnancy Physical Activity Questionnaire was used to assess the physical activity level of women during the three trimesters. A higher level of total physical activity was defined as meeting or exceeding the cohort-specific 75th percentile, and a higher level of exercise was defined according to the Physical Activity Guidelines for Americans. Fetal growth disorder was defined as small-for-gestational age (SGA) or large-for-gestational age (LGA) at birth.
RESULTS: Of the neonates included in this study, 7.1% were SGA and 15.5% were LGA. A higher level of total physical activity during the first trimester (adjusted relative risk (aRR), 0.62 (95% CI, 0.42-0.91)) and second trimester (aRR, 0.62 (95% CI, 0.41-0.95)) was associated with a lower risk of SGA, and a higher level of total physical activity during the third trimester was associated with a lower risk of LGA (aRR, 0.73 (95% CI, 0.54-0.97)). When analyzing physical activity by subtype, a higher level of occupational physical activity during the first and second trimesters was associated negatively with SGA risk, and higher levels of occupational and low-intensity physical activity during the first trimester were associated negatively with LGA risk. No significant association was found between maternal adherence to the Physical Activity Guidelines for Americans and risk of fetal growth disorders.
CONCLUSIONS: A higher total physical activity level during the first and second trimesters was associated with a decreased risk of SGA, whereas a higher total physical activity level in the third trimester was associated with a decreased risk of LGA. Pregnant women should be advised to increase their total physical activity levels instead of focusing on engaging in only moderate-to-vigorous exercise. © 2024 International Society of Ultrasound in Obstetrics and Gynecology.
摘要：
目的：探讨孕妇总体力活动水平与中、剧烈运动与胎儿生长障碍之间的关系。
方法：我们分析了参加中国医科大学纵向出生队列研究的2062对母儿。使用妊娠体力活动问卷评估三个月期间妇女的体力活动水平。较高水平的总体力活动被定义为达到或超过队列特定的第75百分位数，根据美国人的身体活动指南定义了更高水平的运动。胎儿生长障碍定义为出生时小于胎龄（SGA）或大于胎龄（LGA）。
结果：本研究纳入的新生儿中，7.1%为SGA,15.5%为LGA。妊娠早期总体力活动水平较高(调整后相对风险(aRR)，0.62(95%CI，0.42-0.91))和孕中期(aRR，0.62(95%CI，0.41-0.95))与SGA风险较低相关，在妊娠晚期，较高的总体力活动水平与较低的LGA风险相关(aRR，0.73（95%CI，0.54-0.97））。按亚型分析体力活动时，在孕早期和中期，较高水平的职业体力活动与SGA风险呈负相关，妊娠早期较高水平的职业性和低强度体力活动与LGA风险呈负相关。母亲遵守美国人身体活动指南与胎儿生长障碍的风险之间没有显着关联。
结论：孕早期和中期较高的总体力活动水平与SGA风险降低相关，而妊娠晚期较高的总体力活动水平与LGA风险降低相关。应建议孕妇增加其总身体活动水平，而不是只专注于进行中等至剧烈运动。©2024国际妇产科超声学会。
方法：我们分析了参加中国医科大学纵向出生队列研究的2062对母儿。使用妊娠体力活动问卷评估三个月期间妇女的体力活动水平。较高水平的总体力活动被定义为达到或超过队列特定的第75百分位数，根据美国人的身体活动指南定义了更高水平的运动。胎儿生长障碍定义为出生时小于胎龄（SGA）或大于胎龄（LGA）。
结果：本研究纳入的新生儿中，7.1%为SGA,15.5%为LGA。妊娠早期总体力活动水平较高(调整后相对风险(aRR)，0.62(95%CI，0.42-0.91))和孕中期(aRR，0.62(95%CI，0.41-0.95))与SGA风险较低相关，在妊娠晚期，较高的总体力活动水平与较低的LGA风险相关(aRR，0.73（95%CI，0.54-0.97））。按亚型分析体力活动时，在孕早期和中期，较高水平的职业体力活动与SGA风险呈负相关，妊娠早期较高水平的职业性和低强度体力活动与LGA风险呈负相关。母亲遵守美国人身体活动指南与胎儿生长障碍的风险之间没有显着关联。
结论：孕早期和中期较高的总体力活动水平与SGA风险降低相关，而妊娠晚期较高的总体力活动水平与LGA风险降低相关。应建议孕妇增加其总身体活动水平，而不是只专注于进行中等至剧烈运动。©2024国际妇产科超声学会。
