阻断平滑的胆固醇化 : 克服癌症耐药性的策略。
Mesh : Humans Smoothened Receptor / antagonists & inhibitors metabolism Drug Resistance, Neoplasm / drug effects Cholesterol / metabolism chemistry Diterpenes / pharmacology chemistry Hedgehog Proteins / metabolism antagonists & inhibitors Neoplasms / drug therapy metabolism pathology Animals Receptors, G-Protein-Coupled / metabolism antagonists & inhibitors Antineoplastic Agents / pharmacology chemistry Signal Transduction / drug effects
来 源: DOI:10.1016/j.chembiol.2024.06.005