关键词: Erk mTOR protein synthesis skeletal muscle succinate

来  源:   DOI:10.3892/mmr.2024.13293   PDF(Pubmed)

Abstract:
Following the publication of the above article, the authors realized that, in Fig. 1D on p. 7363, the data panel selected for the \'0.5 mM Succinate\' group was duplicated in Fig. 1B (Control) in another article of theirs published in FASEB J (\"α‑Ketoglutarate prevents skeletal muscle protein degradation and muscle atrophy through PHD3/ADRB2 pathway\": doi: 10.1096/fj.201700670R) due to the fact that they had inadvertently confused the layout of the two figures. The authors apologize for this error. Secondly, in terms of the quantification of the blots shown in Fig. 2A, β‑actin was not in fact used as a loading control; the phosphoproteins were normalized against the levels of the relative total protein, and the layout of Fig. 2A has been revised to reflect this (note that the the figure legend for Fig. 2 has also been revised: The last sentence no longer reads, \"β‑actin was used as a loading control.\"). The revised versions of Figs. 1 and 2 are shown on the next page. Note that these errors did not affect the results or the main conclusions reported in the study, and no corrections were required either to the descriptions in the text or to the histograms shown in these figures. All the authors approve of the publication of this corrigendum, and the authors are grateful to the Editor of Molecular Medicine Reports for allowing them the opportunity to publish this. The authors regret their oversight in allowing these errors to be included in the paper, and apologize to the readership for any inconvenience caused. [Molecular Medicine Reports 16: 7361‑7366, 2017; DOI: 10.3892/mmr.2017.7554].
摘要:
上述文章发表后,作者意识到,在图中。在图1D的第7363页上,为“0.5mM琥珀酸盐”组选择的数据面板在图1D中重复。1B(对照)在他们发表在FASEBJ上的另一篇文章中(“α-酮戊二酸通过PHD3/ADRB2途径防止骨骼肌蛋白降解和肌肉萎缩”:doi:10.1096/fj.201700670R),因为他们无意中混淆了两个数字的布局。作者为这个错误道歉。其次,就图中所示的印迹的定量而言。2A,β-肌动蛋白实际上没有用作加载对照;磷蛋白相对于相对总蛋白的水平进行归一化,和无花果的布局。已对2A进行了修订以反映这一点(请注意,图的图例。2也修改了:最后一句不再是,“β-肌动蛋白用作加载对照。\")。无花果的修订版。1和2显示在下一页。请注意,这些错误不会影响研究中报告的结果或主要结论,并且不需要对文本中的描述或这些图中所示的直方图进行更正。所有作者都赞成本更正的出版,作者感谢《分子医学报告》的编辑让他们有机会发表这篇文章。作者感到遗憾的是,他们的疏忽允许这些错误被包括在论文中,并对造成的不便向读者道歉。[分子医学报告16:7361-7366,2017;DOI:10.3892/mmr.2017.7554]。
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