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Abstract：
OBJECTIVE: This study aimed to examine the impact of leukemia and other cancers in India and to observe any changes over time.
METHODS: Detailed estimates of incidence, prevalence, mortality, and disability-adjusted life years (DALYs) for 30 types of cancers in India were analyzed for 29 years from 1990 to 2019 as part of the Global Burden of Diseases (GBD) study. Data from all available sources were used to gather information on the overall burden of disease in India.
RESULTS: Cancer is a leading cause of death worldwide, with varying rates of incidence in India, making prevention and treatment a challenge. Because cancer is not a reportable disease in India, the overall burden estimate is still a work in progress. This study analyzed the impact of leukemia and other cancers in India, including trends in incidence, DALYs, and mortality related to all cancers and various malignancies. The causes of leukemia in India were also explored.
CONCLUSIONS: The study found the trends of cancer types that account for the majority of leukemia-related and cancer-related DALYs, death, prevalence, and incidence in India. Among the four most frequent malignancies, such as leukemia, there was significant variation based on age. Over the last 29 years, mortality from chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL) has decreased, while deaths from acute myelogenous leukemia (AML) and chronic lymphocytic leukemia (CLL) have increased steadily.
METHODS: Detailed estimates of incidence, prevalence, mortality, and disability-adjusted life years (DALYs) for 30 types of cancers in India were analyzed for 29 years from 1990 to 2019 as part of the Global Burden of Diseases (GBD) study. Data from all available sources were used to gather information on the overall burden of disease in India.
RESULTS: Cancer is a leading cause of death worldwide, with varying rates of incidence in India, making prevention and treatment a challenge. Because cancer is not a reportable disease in India, the overall burden estimate is still a work in progress. This study analyzed the impact of leukemia and other cancers in India, including trends in incidence, DALYs, and mortality related to all cancers and various malignancies. The causes of leukemia in India were also explored.
CONCLUSIONS: The study found the trends of cancer types that account for the majority of leukemia-related and cancer-related DALYs, death, prevalence, and incidence in India. Among the four most frequent malignancies, such as leukemia, there was significant variation based on age. Over the last 29 years, mortality from chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL) has decreased, while deaths from acute myelogenous leukemia (AML) and chronic lymphocytic leukemia (CLL) have increased steadily.
摘要：
目的：这项研究旨在检查印度白血病和其他癌症的影响，并观察随时间的变化。
方法：详细估计发病率，患病率,死亡率,作为全球疾病负担（GBD）研究的一部分，从1990年到2019年，对印度30种癌症的残疾调整寿命年（DALYs）进行了29年的分析。来自所有可用来源的数据用于收集有关印度疾病总体负担的信息。
结果：癌症是全球死亡的主要原因，印度的发病率不同，使预防和治疗成为挑战。因为癌症在印度不是可报告的疾病，总体负担估计仍在进行中。这项研究分析了白血病和其他癌症在印度的影响，包括发病率趋势，DALYs,和死亡率与所有癌症和各种恶性肿瘤有关。还探讨了印度白血病的病因。
结论：该研究发现了占大多数白血病相关和癌症相关DALYs的癌症类型的趋势，死亡,患病率,以及印度的发病率。在四种最常见的恶性肿瘤中，比如白血病，根据年龄有显著差异。在过去的29年里,慢性粒细胞白血病（CML）和急性淋巴细胞白血病（ALL）的死亡率有所下降，而急性髓细胞性白血病（AML）和慢性淋巴细胞性白血病（CLL）的死亡人数稳步增加。
方法：详细估计发病率，患病率,死亡率,作为全球疾病负担（GBD）研究的一部分，从1990年到2019年，对印度30种癌症的残疾调整寿命年（DALYs）进行了29年的分析。来自所有可用来源的数据用于收集有关印度疾病总体负担的信息。
结果：癌症是全球死亡的主要原因，印度的发病率不同，使预防和治疗成为挑战。因为癌症在印度不是可报告的疾病，总体负担估计仍在进行中。这项研究分析了白血病和其他癌症在印度的影响，包括发病率趋势，DALYs,和死亡率与所有癌症和各种恶性肿瘤有关。还探讨了印度白血病的病因。
结论：该研究发现了占大多数白血病相关和癌症相关DALYs的癌症类型的趋势，死亡,患病率,以及印度的发病率。在四种最常见的恶性肿瘤中，比如白血病，根据年龄有显著差异。在过去的29年里,慢性粒细胞白血病（CML）和急性淋巴细胞白血病（ALL）的死亡率有所下降，而急性髓细胞性白血病（AML）和慢性淋巴细胞性白血病（CLL）的死亡人数稳步增加。
