关键词: SARC-F questionnaire Vietnam cardiovascular disease mortality sarcopenia

来  源:   DOI:10.3389/fmed.2024.1406007   PDF(Pubmed)

Abstract:
UNASSIGNED: Older patients typically face elevated mortality rates and greater medical resource utilization during hospitalizations compared to their younger counterparts. Sarcopenia, serving as a prognostic indicator, is related to disability, diminished quality of life, and increased mortality. The SARC-F questionnaire, known for its cost-effectiveness, offers a valuable means of assessing sarcopenia. This study aims to explore the association between SARC-F scores and risk of adverse outcomes in elderly patients with cardiovascular disease at a Ho Chi Minh City hospital.
UNASSIGNED: Participants aged 60 and above, admitted to the Department of Cardiology - Interventional and Cardiovascular Emergency of Thong Nhat Hospital in Ho Chi Minh City from November 2021 to June 2022, were recruited for the prospective, single-center study. The prognostic outcomes included all-cause death and the initial occurrence of emergency re-hospitalization within 6 months\' post-discharge. The Kaplan-Meier analysis compared the overall survival rates between different SARC-F score groups.
UNASSIGNED: The study enrolled 285 patients with a median age of 74 (67, 81). During a 6-month follow-up period, there were 14 cases of mortality. A SARC-F score of 4 or higher was significantly associated with an increased risk of all-cause mortality, with HR of 2.02 (95% CI: 1.39-2.92, p < 0.001), and higher incidence of re-hospitalization events with RR of 1.66 (95% CI: 1.06 to 2.59, p = 0.026). Kaplan-Meier survival analysis indicated a notably higher mortality rate in the patients with high SARC-F scores (p < 0.001).
UNASSIGNED: In elderly patients with cardiovascular disease, the SARC-F questionnaire could serve as a simple and cost-effective method for detecting mortality and the risk of re-hospitalization.
摘要:
与年轻患者相比,老年患者在住院期间通常面临较高的死亡率和更高的医疗资源利用率。肌肉减少症,作为预后指标,与残疾有关,生活质量下降,和死亡率增加。SARC-F问卷,以其成本效益而闻名,提供了一种评估肌少症的有价值的手段。本研究旨在探讨SARC-F评分与胡志明市医院老年心血管疾病患者不良后果风险之间的关系。
60岁及以上的参与者,从2021年11月至2022年6月被胡志明市ThongNhat医院心脏病学-介入和心血管急诊部门录取,单中心研究。预后结果包括全因死亡和出院后6个月内急诊再次住院的初始发生。Kaplan-Meier分析比较了不同SARC-F评分组之间的总生存率。
该研究招募了285名患者,中位年龄为74岁(67,81)。在6个月的随访期间,有14例死亡。SARC-F评分为4或更高与全因死亡风险增加显著相关,HR为2.02(95%CI:1.39-2.92,p<0.001),再住院事件发生率较高,RR为1.66(95%CI:1.06~2.59,p=0.026)。Kaplan-Meier生存分析显示SARC-F评分高的患者死亡率明显较高(p<0.001)。
老年心血管疾病患者,SARC-F问卷可作为检测死亡率和再住院风险的简单且经济有效的方法.
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