PDF(Pubmed)
Abstract：
Biliary atresia (BA) is a congenital disease that occurs when extrahepatic bile ducts are either absent or deficient, resulting in liver fibrosis, portal hypertension, and eventually cirrhosis. It is the most common cause of persistent obstructive jaundice in newborns lasting more than two weeks is this condition. Abdominal ultrasound (US) is the primary imaging technique used to diagnose BA, while computed tomography (CT) is reserved for more complex cases. The gold standard for diagnosing BA is still intraoperative cholangiogram with liver biopsy. Treatment for BA usually involves Kasai hepatoportoenterostomy, but some patients still require liver transplantation due to diagnostic delays and advanced disease. In this study, the authors present the case of a 3-month-old infant with biliary atresia and its ultrasound characteristics, who underwent liver transplantation due to advanced disease. The primary objective of imaging is to provide a prompt diagnosis, given the crucial significance of timely surgical intervention.
摘要：
胆道闭锁（BA）是一种先天性疾病，发生在肝外胆管缺失或缺乏时，导致肝纤维化，门静脉高压症,最后是肝硬化.这种情况是持续超过两周的新生儿持续阻塞性黄疸的最常见原因。腹部超声（US）是用于诊断BA的主要成像技术，而计算机断层扫描（CT）保留用于更复杂的病例。诊断BA的金标准仍然是肝活检术中胆管造影。BA的治疗通常包括Kasai肝肠造口术，但是由于诊断延迟和疾病进展，一些患者仍然需要肝移植。在这项研究中,作者介绍了一个3个月大的婴儿胆道闭锁的病例及其超声特征，由于晚期疾病接受了肝移植。成像的主要目的是提供及时的诊断，鉴于及时手术干预的重要意义。
