激活素受体样激酶 1 和 2 的两种高度选择性结构正交化学探针的发现。
Mesh : Animals Humans Mice Activin Receptors, Type II / metabolism antagonists & inhibitors Activin Receptors, Type I / antagonists & inhibitors metabolism Protein Kinase Inhibitors / pharmacology chemistry Structure-Activity Relationship Signal Transduction / drug effects Drug Discovery Molecular Probes / chemistry Bone Morphogenetic Proteins / metabolism Pyrazoles / chemistry pharmacology chemical synthesis
来 源:
DOI:10.1021/acs.jmedchem.4c00629
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