关键词: clinical study dogs histopathology localisation tumours

来  源:   DOI:10.17221/16/2024-VETMED   PDF(Pubmed)

Abstract:
The aim of this study is to investigate the correlation between the incidence of spontaneous tumours of various origins and the localisation in dogs with sex, breed, and age factors. A total of 360 tumours with various localisation were studied pathomorphologically. Histopathologic data sets from 360 dog tissue samples were processed and statistically examined. A chi-square test of independence was conducted to examine the relationships among the various levels of the specified variables. Logistic regression models were employed for dichotomous outcomes to ascertain the influence of certain explanatory variables on the tumour types. Characteristic pathomorphological changes observed during examination of dogs with oncologic diseases were determined. The most common neoplasms were mammary tumours, accounting for 43% of the cases. The mammary gland tumours were most common in mongrel dogs (25%), with German Shepherds (17.3%), Poodles, Dachshunds, Central Asian Shepherds (6.7% each), and Rottweilers (5.7%) following. The highest frequency of these tumours appeared at 8 years of age, predominantly originating from the ductal epithelium, which represented 46.4% of all the malignant cases.
摘要:
这项研究的目的是调查各种起源的自发性肿瘤的发生率与性别犬的定位之间的相关性,品种,和年龄因素。对总共360例具有不同定位的肿瘤进行了病理形态学研究。处理来自360个狗组织样品的组织病理学数据集并进行统计学检查。进行了独立性的卡方检验,以检查指定变量的各个级别之间的关系。采用Logistic回归模型进行二分结果,以确定某些解释变量对肿瘤类型的影响。确定了在检查肿瘤疾病犬期间观察到的特征性病理形态学变化。最常见的肿瘤是乳腺肿瘤,占病例的43%。乳腺肿瘤在杂种犬中最常见(25%),德国牧羊犬(17.3%)贵宾犬,腊肠,中亚牧羊人(各6.7%),和罗威纳犬(5.7%)紧随其后。这些肿瘤的最高频率出现在8岁时,主要起源于导管上皮,占所有恶性肿瘤的46.4%。
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