关键词: Cicatrix hypertrophic mast cells rhinitis turbinates wound healing

来  源:   DOI:10.14744/SEMB.2024.78785   PDF(Pubmed)

Abstract:
UNASSIGNED: This study aimed to investigate the presence and severity of inferior turbinate hypertrophy (ITH) in patients with hypertrophic scars (HTS).
UNASSIGNED: This case-control study was conducted with patients diagnosed with HTS during dermatologic examination and a control group without HTS. An otolaryngologist evaluated the presence and severity of inferior turbinate hypertrophy by anterior rhinoscopy.
UNASSIGNED: ITH was more common in patients with HTS compared to the control group (64%, and 34%, respectively) (p=0.014). In the HTS group, 48% of patients had grade 2, and 16% had grade 3 ITH; in the control group, 24% had grade 2, and 10% had grade 3 ITH (p=0.046). Also, ITH was higher in patients who complained of pruritus or pain (83%, and 80%, respectively) in the HTS than in asymptomatic HTS patients (p=0.020).
UNASSIGNED: A higher number of patients with HTS had ITH compared to the control group, especially those who reported pruritus or pain associated with scar. Given the limited understanding of the full pathogenesis and treatment of HTS and ITH, their association potentially provides new insights into these related conditions.
摘要:
本研究旨在调查肥厚性瘢痕(HTS)患者下鼻甲肥大(ITH)的存在和严重程度。
本病例对照研究是对在皮肤病学检查中诊断为HTS的患者和没有HTS的对照组进行的。耳鼻喉科医师通过前鼻镜检查评估下鼻甲肥大的存在和严重程度。
ITH在HTS患者中比对照组更常见(64%,34%,分别)(p=0.014)。在HTS组中,48%的患者为2级,16%的患者为3级;在对照组中,24%为2级,10%为3级(p=0.046)。此外,抱怨瘙痒或疼痛的患者ITH较高(83%,80%,分别)在HTS中高于无症状HTS患者(p=0.020)。
与对照组相比,HTS患者的ITH数量更高,尤其是那些报告与疤痕相关的瘙痒或疼痛的人。鉴于对HTS和ITH的全部发病机制和治疗的了解有限,它们的关联可能为这些相关条件提供新的见解。
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