关键词: COVID-19 alopecia areata correlation pathogenesis treatment vaccination

Mesh : Alopecia Areata / epidemiology immunology Humans COVID-19 / immunology epidemiology SARS-CoV-2 / immunology COVID-19 Vaccines / immunology

来  源:   DOI:10.3389/fimmu.2024.1347311   PDF(Pubmed)

Abstract:
Corona virus disease 2019(COVID-19) is one of the most serious respiratory pandemic diseases threatening human health for centuries. Alopecia areata (AA) is a sudden patchy hair loss, an autoimmune disease, which seriously affects the image and mental health of patients. Evidence shows that the risk of autoimmune diseases significantly increases after COVID-19, and is positively correlated with the severity, with a significant increase in the risk of alopecia in those over 40 years old. The relationship between COVID-19 and AA has become a hot topic of current research. Strengthening the research on the correlation between COVID-19 and AA can help to identify and protect susceptible populations at an early stage. This article reviews the research progress on the epidemiological background of COVID-19 and AA, the situation and possible mechanisms of AA induced by COVID-19 or COVID-19 vaccination, and potential treatment methods.
摘要:
冠状病毒病2019(COVID-19)是几个世纪以来威胁人类健康的最严重的呼吸道流行病之一。斑秃(AA)是一种突然的斑片状脱发,一种自身免疫性疾病,严重影响患者的形象和心理健康。证据表明,COVID-19后自身免疫性疾病的风险显著增加,且与严重程度呈正相关,在40岁以上的人群中,脱发的风险显着增加。COVID-19与AA的关系已成为当前研究的热点。加强对COVID-19与AA相关性的研究有助于早期识别和保护易感人群。本文综述了COVID-19和AA的流行病学背景研究进展,COVID-19或COVID-19疫苗诱导AA的情况和可能的机制,和潜在的治疗方法。
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