This prospective randomized study involved sixty patients who underwent gynecomastia surgery. Individuals were randomly divided into two groups: the RISS group (N.=30) and the control group (N.=30). After anesthesia induction, the patients received bilateral US-RISS using 40 mL of 0.25% levobupivacaine, or conventional intravenous analgesia with no intervention, respectively. The primary outcome was the overall morphine consumption in 24 hours, and the secondary endpoints involved the time elapsed till rescue analgesia was requested, the quality of recovery after 24 hours and side effects\' incidence.
Morphine consumption was noticeably decreased in the RISS group compared to the control group, with 14.07±4.91 mg and 35.83±1.70 mg mean values, respectively (P<0.001). Furthermore, in the RISS group, the initial rescue analgesia request occurred significantly later than in the control group, with mean values of 15.58±1.41 hours and 0.96±0.63 hours, respectively (P<0.001). Additionally, within the RISS group, there was a high quality of recovery observed, with a low incidence of opioid-related adverse events in comparison to the control group.
Bilateral US-RISS block is a beneficial intervention in gynecomastia surgery for pain management and improves the quality of recovery.
方法:这项前瞻性随机研究纳入了60例男性乳房发育手术患者。个人随机分为两组:RISS组(N.=30)和对照组(N。=30)。麻醉诱导后,患者接受使用40毫升0.25%左旋布比卡因的双侧US-RISS,或无干预的常规静脉镇痛,分别。主要结果是24小时内吗啡的总体消耗,次要终点涉及到要求抢救镇痛的时间,24小时后恢复的质量和副作用的发生率。
结果:与对照组相比,RISS组的吗啡消耗量明显降低,平均值为14.07±4.91毫克和35.83±1.70毫克,分别(P<0.001)。此外,在RISS组中,初次抢救镇痛要求明显晚于对照组,平均值为15.58±1.41小时和0.96±0.63小时,分别(P<0.001)。此外,在RISS组中,观察到高质量的恢复,与对照组相比,阿片类药物相关不良事件的发生率较低。
结论:双侧US-RISS阻滞是妇科乳房发育手术中疼痛管理的有益干预措施,可提高康复质量。