Abstract：
BACKGROUND: Anatomical evidence reveals heterogeneous fat distribution in both atrial and ventricular myocardium that are considered normal, but at the same time arrhythmogenic, and numerous cardiac pathophysiological conditions are associated with myocardial fat deposits. The relationship between fatty infiltration, especially in the epicardial layer and its pathophysiological implication is not completely understood.
OBJECTIVE: The aim of this study was to establish a positive or negative relationship between the ventricular burden and several parameters related to right ventricle (RV) adipose tissue - the RV thickness, RV indexed mass, body mass index (BMI), age, gender.
METHODS: Twenty-three patients with documented premature ventricular contractions (PVCs) originating from right ventricular outflow tract based on electrocardiography (ECG) evaluation were hospitalized between January 2018-November 2022 for electrophysiological study and PVCs ablation. Data obtained after collecting the clinical characteristics, ECG, RV measurements from transthoracic echocardiography (TTE), cardiac computed tomography (CT) and magnetic resonance imaging (MRI) were analyzed.
RESULTS: A weak positive relationship between the ventricular burden and BMI (r=0.14, p=0.49), tricuspid annular plane systolic excursion (TAPSE) (r=0.07, p=0.7), the RV thickness (r=0.03, p=0.8), epicardial adipose tissue (r=0.13, p=0.55), RV mass indexed (r=0.05, p=0.82) was observed. No clear cut-off of the PVCs burden could be established in terms related to the increase in BMI, RV thickness, epicardial adipose tissue, RV mass indexed.
CONCLUSIONS: No significant positive or negative relationship between the ventricular burden and the RV thickness, RV indexed mass were found in individuals with a high PVCs originating from right ventricular outflow tract (RVOT) burden.
OBJECTIVE: The aim of this study was to establish a positive or negative relationship between the ventricular burden and several parameters related to right ventricle (RV) adipose tissue - the RV thickness, RV indexed mass, body mass index (BMI), age, gender.
METHODS: Twenty-three patients with documented premature ventricular contractions (PVCs) originating from right ventricular outflow tract based on electrocardiography (ECG) evaluation were hospitalized between January 2018-November 2022 for electrophysiological study and PVCs ablation. Data obtained after collecting the clinical characteristics, ECG, RV measurements from transthoracic echocardiography (TTE), cardiac computed tomography (CT) and magnetic resonance imaging (MRI) were analyzed.
RESULTS: A weak positive relationship between the ventricular burden and BMI (r=0.14, p=0.49), tricuspid annular plane systolic excursion (TAPSE) (r=0.07, p=0.7), the RV thickness (r=0.03, p=0.8), epicardial adipose tissue (r=0.13, p=0.55), RV mass indexed (r=0.05, p=0.82) was observed. No clear cut-off of the PVCs burden could be established in terms related to the increase in BMI, RV thickness, epicardial adipose tissue, RV mass indexed.
CONCLUSIONS: No significant positive or negative relationship between the ventricular burden and the RV thickness, RV indexed mass were found in individuals with a high PVCs originating from right ventricular outflow tract (RVOT) burden.
摘要：
背景：解剖学证据显示心房和心室心肌中脂肪分布不均，被认为是正常的，但同时会导致心律失常，许多心脏病理生理状况与心肌脂肪沉积有关。脂肪浸润之间的关系，特别是在心外膜层，其病理生理意义尚不完全清楚。
目的：这项研究的目的是在心室负荷与与右心室（RV）脂肪组织相关的几个参数之间建立正或负的关系-RV厚度，RV指数质量，体重指数（BMI），年龄,gender.
方法：在2018年1月至2022年11月期间，根据心电图（ECG）评估，有23例记录的源自右心室流出道的室性早搏（PVC）患者住院，进行电生理研究和PVC消融。收集临床特征后获得的数据，心电图,经胸超声心动图(TTE)右心室测量值,分析了心脏计算机断层扫描（CT）和磁共振成像（MRI）。
结果：心室负荷与BMI之间存在微弱的正相关关系（r=0.14，p=0.49），三尖瓣环平面收缩期偏移（TAPSE）（r=0.07，p=0.7），RV厚度(r=0.03，p=0.8)，心外膜脂肪组织(r=0.13,p=0.55),观察到RV质量指数（r=0.05，p=0.82）。根据BMI的增加，无法确定PVC负担的明确界限，RV厚度,心外膜脂肪组织，RV质量指标。
结论：心室负荷与右心室厚度之间没有显著的正相关或负相关，右心室流出道（RVOT）负担较高的PVC个体中发现了RV指数质量。
目的：这项研究的目的是在心室负荷与与右心室（RV）脂肪组织相关的几个参数之间建立正或负的关系-RV厚度，RV指数质量，体重指数（BMI），年龄,gender.
方法：在2018年1月至2022年11月期间，根据心电图（ECG）评估，有23例记录的源自右心室流出道的室性早搏（PVC）患者住院，进行电生理研究和PVC消融。收集临床特征后获得的数据，心电图,经胸超声心动图(TTE)右心室测量值,分析了心脏计算机断层扫描（CT）和磁共振成像（MRI）。
结果：心室负荷与BMI之间存在微弱的正相关关系（r=0.14，p=0.49），三尖瓣环平面收缩期偏移（TAPSE）（r=0.07，p=0.7），RV厚度(r=0.03，p=0.8)，心外膜脂肪组织(r=0.13,p=0.55),观察到RV质量指数（r=0.05，p=0.82）。根据BMI的增加，无法确定PVC负担的明确界限，RV厚度,心外膜脂肪组织，RV质量指标。
结论：心室负荷与右心室厚度之间没有显著的正相关或负相关，右心室流出道（RVOT）负担较高的PVC个体中发现了RV指数质量。
