UNASSIGNED: We gathered clinical characteristics, intraoperative data, postoperative outcomes, and prognosis information from PAS patients who underwent surgical treatment at our institution between December 2016 and September 2023.
UNASSIGNED: A total of 20 patients with PAS underwent pulmonary endarterectomy. The median age of the patients was 52 (IQR 45, 57) years, with 12 patients (60%) being female. Intimal sarcoma was confirmed in 19 patients, while the remaining one was diagnosed with large cell neuroendocrine carcinoma. The perioperative mortality rate was three cases (15%). Follow-up was conducted for a median duration of 14 months (range: 1-61). During the follow-up period, 11 patients experienced recurrence or metastasis, and 5 patients succumbed to the disease. The estimated cumulative survival rates at 1 and 2 years for all 20 patients were 66.4% and 55.3%, respectively.
UNASSIGNED: Pulmonary endarterectomy emerges as a palliative but effective approach for managing PAS, particularly when complemented with postoperative therapies such as chemotherapy and targeted therapy, which collectively contribute to achieving favorable long-term survival outcomes.
■我们收集了临床特征,术中数据,术后结果,以及2016年12月至2023年9月期间在我们机构接受手术治疗的PAS患者的预后信息.
■共有20例PAS患者接受了肺内膜切除术。患者的中位年龄为52岁(IQR45,57),12名患者(60%)为女性。在19例患者中证实了内膜肉瘤,其余1例被诊断为大细胞神经内分泌癌。围手术期死亡率为3例(15%)。随访的中位时间为14个月(范围:1-61)。在后续期间,11例患者复发或转移,5名患者死于该病。所有20例患者的1年和2年累积生存率分别为66.4%和55.3%。分别。
■肺动脉内膜切除术是治疗PAS的一种姑息但有效的方法,特别是当辅以术后治疗如化疗和靶向治疗时,它们共同有助于实现有利的长期生存结果。