关键词: Heart assessment Heart transplant Imaging techniques Magnetic resonance imaging Spectroscopy Ultrasound

来  源:   DOI:10.1007/s40472-023-00400-w   PDF(Pubmed)

Abstract:
UNASSIGNED: The current lack of objective and quantitative assessment techniques to determine cardiac graft relative viability results in risk-averse decision-making, which negatively impact the utilization of cardiac grafts. The purpose of this review is to highlight the current deficiencies in cardiac allograft assessment before focusing on novel cardiac assessment techniques that exploit conventional and emerging imaging modalities, including ultrasound, magnetic resonance, and spectroscopy.
UNASSIGNED: Extensive work is ongoing by the scientific community to identify improved objective metrics and tools for cardiac graft assessment, with the goal to safely increasing the number and proportion of hearts accepted for transplantation.
UNASSIGNED: This review briefly discusses the in situ and ex vivo tools currently available for clinical organ assessment, before focusing on the individual capabilities of ultrasound, magnetic resonance, and spectroscopy to provide insightful, non-invasive information regarding cardiac graft functional and metabolic status that may be used to predict outcome after transplantation.
摘要:
当前缺乏客观和定量的评估技术来确定心脏移植物的相对生存力,导致了规避风险的决策。这对心脏移植物的利用产生了负面影响。这篇综述的目的是在关注利用传统和新兴成像模式的新型心脏评估技术之前,强调目前心脏同种异体移植评估的不足。包括超声波,磁共振,和光谱学。
科学界正在开展广泛的工作,以确定用于心脏移植评估的改进的客观指标和工具。目的是安全地增加接受移植的心脏的数量和比例。
这篇综述简要讨论了目前可用于临床器官评估的原位和离体工具,在关注超声波的个人能力之前,磁共振,和光谱学提供有洞察力的,关于心脏移植物功能和代谢状态的非侵入性信息,可用于预测移植后的结果。
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