METHODS: This was a prospective study of 134 hemodialysis patients. The level of fatigue was evaluated using a visual analog scale (VAS). The association between high fatigue evaluated by the highest quartile of the VAS value and all-cause death was investigated.
RESULTS: The fatigue scale score was significantly higher on dialysis than on non-dialysis days. During the follow-up period (median 6.8 years), 42 patients died. Patients with high post-dialysis fatigue in the higher quartiles died more frequently compared to those with in the lower quartiles (p = 0.012). Multivariate Cox regression analysis showed that high post-dialysis fatigue was an independent predictor of all-cause death (adjusted hazard ratio 2.12, 95% confidence interval 1.10-4.07).
CONCLUSIONS: Higher post-dialysis fatigue is related to increased mortality.
方法:这是一项针对134名血液透析患者的前瞻性研究。使用视觉模拟量表(VAS)评估疲劳水平。研究了通过VAS值的最高四分位数评估的高度疲劳与全因死亡之间的关联。
结果:透析天数的疲劳量表评分明显高于非透析天数。在随访期间(中位数为6.8年),42名患者死亡。与较低四分位数的患者相比,较高四分位数的透析后疲劳患者死亡频率更高(p=0.012)。多因素Cox回归分析显示透析后高疲劳度是全因死亡的独立预测因子(调整后风险比2.12,95%置信区间1.10-4.07)。
结论:较高的透析后疲劳与死亡率增加有关。