%0 Journal Article
%T Post-dialysis fatigue predicts all-cause mortality in patients on chronic hemodialysis.
%A Watanabe G
%A Tanaka K
%A Saito H
%A Kimura H
%A Tani Y
%A Asai J
%A Suzuki H
%A Sato K
%A Nakayama M
%A Kazama JJ
%J Ther Apher Dial
%V 0
%N 0
%D 2024 Jul 16
%M 39013552
%F 2.195
%R 10.1111/1744-9987.14186
%X <B>BACKGROUND: </B>Fatigue is reportedly associated with a poor prognosis in dialysis patients. The aim of the present study was to investigate whether fatigue on dialysis days or non-dialysis days is associated with mortality in patients on chronic hemodialysis.<BR><B>METHODS: </B>This was a prospective study of 134 hemodialysis patients. The level of fatigue was evaluated using a visual analog scale (VAS). The association between high fatigue evaluated by the highest quartile of the VAS value and all-cause death was investigated.<BR><B>RESULTS: </B>The fatigue scale score was significantly higher on dialysis than on non-dialysis days. During the follow-up period (median 6.8 years), 42 patients died. Patients with high post-dialysis fatigue in the higher quartiles died more frequently compared to those with in the lower quartiles (p = 0.012). Multivariate Cox regression analysis showed that high post-dialysis fatigue was an independent predictor of all-cause death (adjusted hazard ratio 2.12, 95% confidence interval 1.10-4.07).<BR><B>CONCLUSIONS: </B>Higher post-dialysis fatigue is related to increased mortality.