Abstract:
A neuroelectrode can be easily prepared using a wet-spun fiber of D-sorbitol/PEDOT:PSS. At a D-sorbitol/PEDOT:PSS weight ratio of 6, the fiber is well-modulated with suitable characters, including the morphology, crystallization, diffusion resistance (179 kΩ), and electric double-layer capacitance (2.72 μF), for sensitive recording of brain activity during somatosensory stimulation and seizures. Additionally, the fiber is highly biocompatible with the brain. This study presents a simple and controllable strategy for the chemical construction of conducting polymer-based neurosensors.
摘要:
神经电极可以使用D-山梨糖醇/PEDOT:PSS的湿纺纤维容易地制备。在D-山梨糖醇/PEDOT:PSS重量比为6时,纤维被很好地调制,具有合适的特性,包括形态学,结晶,扩散电阻(179kΩ),和双电层电容(2.72μF),用于体感刺激和癫痫发作期间大脑活动的敏感记录。此外,这种纤维与大脑具有高度的生物相容性。这项研究为导电聚合物基神经传感器的化学构建提供了一种简单可控的策略。