PDF(Pubmed)
Abstract：
Anabolic androgenic steroids (AAS) are relatively cheap and accessible medications, commonly used by athletes and bodybuilders for performance enhancement and muscle growth stimulation. AAS usage has been associated with musculoskeletal injuries, such as tendon and ligament ruptures, and numerous other detrimental health effects. Despite these risks, individuals continue to self-administer these drugs in supraphysiologic doses. Here, we present a case of a male bodybuilder with chronic AAS use who developed a spinal thoracic intervertebral disc herniation requiring decompression and fusion. We use this case to highlight a severe potential risk associated with chronic AAS abuse and review the current literature on the biochemical, physical, and physiologic mechanisms linking chronic AAS use, weight-bearing exercise, and the risk of musculoskeletal injuries such as intervertebral disc herniations.
摘要：
合成代谢雄激素类固醇（AAS）是相对便宜和容易获得的药物，运动员和健美运动员通常用于提高性能和刺激肌肉生长。AAS的使用与肌肉骨骼损伤有关，如肌腱和韧带断裂，和许多其他有害的健康影响。尽管存在这些风险,个体继续以超生理剂量自我给药这些药物.这里,我们介绍了一例长期使用AAS的男性健美运动员，他患上了需要减压和融合的胸椎椎间盘突出症。我们使用这个案例来强调与慢性AAS滥用相关的严重潜在风险，并回顾当前关于生化，物理，和连接慢性AAS使用的生理机制，负重运动,以及椎间盘突出等肌肉骨骼损伤的风险。
