Abstract：
Schizophyllum commune is a mushroom-forming fungus notable for its distinctive fruiting bodies with split gills. It is used as a model organism to study mushroom development, lignocellulose degradation and mating type loci. It is a hypervariable species with considerable genetic and phenotypic diversity between the strains. In this study, we systematically phenotyped 16 dikaryotic strains for aspects of mushroom development and 18 monokaryotic strains for lignocellulose degradation. There was considerable heterogeneity among the strains regarding these phenotypes. The majority of the strains developed mushrooms with varying morphologies, although some strains only grew vegetatively under the tested conditions. Growth on various carbon sources showed strain-specific profiles. The genomes of seven monokaryotic strains were sequenced and analyzed together with six previously published genome sequences. Moreover, the related species Schizophyllum fasciatum was sequenced. Although there was considerable genetic variation between the genome assemblies, the genes related to mushroom formation and lignocellulose degradation were well conserved. These sequenced genomes, in combination with the high phenotypic diversity, will provide a solid basis for functional genomics analyses of the strains of S. commune.
摘要：
Schizphyllumcommune是一种蘑菇形成的真菌，以其独特的子实体和裂开的g而著称。它被用作研究蘑菇发育的模式生物，木质纤维素降解和交配型基因座。它是一种超变物种，菌株之间具有相当大的遗传和表型多样性。在这项研究中,在蘑菇发育方面，我们系统地对16个原核菌株进行了表型分析，对18个单核菌株进行了木质纤维素降解。关于这些表型，菌株之间存在相当大的异质性。大多数菌株培养出形态不同的蘑菇，尽管某些菌株仅在测试条件下营养生长。在各种碳源上的生长显示出菌株特异性曲线。对七个单核菌株的基因组进行了测序，并与六个先前发表的基因组序列一起进行了分析。此外，对相关物种筋膜裂竹进行了测序。尽管基因组组装之间存在相当大的遗传变异，与蘑菇形成和木质纤维素降解相关的基因保存良好。这些测序的基因组，结合高表型多样性，将为S.commune菌株的功能基因组学分析提供坚实的基础。
