Abstract：
OBJECTIVE: This study investigated the effects of a soy protein-rich meal intervention on the muscle health of older adults in long-term care facilities.
METHODS: A 12-week single-center randomized controlled trial with a control-group and open-label design was conducted. Eighty-four older adults from a long-term care facility participated in the study. The chefs at the facility cooked three meals using soy protein-rich recipes designed by dieticians. For 12 weeks, the intervention group participants consumed three meals with 30 g of soy protein (10 g/meal) per day, and the control group participants maintained their habitual diets.
RESULTS: The 84 participants (mean age, 84.9 ± 7.0 years; 61.9% female) were randomly assigned to an intervention group (43 participants) and a control group (41 participants). The intervention group exhibited significant increases in several lean mass indicators, namely soft lean mass (mean, 1.43 kg; 95% confidence interval [CI]: 0.20-1.65 kg), skeletal muscle mass (mean, 1.20 kg; 95% CI: 0.43-1.96 kg), appendicular skeletal muscle mass (mean, 0.79 kg; 95% CI: 0.07-1.52 kg), and skeletal muscle index (mean, 0.37 kg/m2; 95% CI: 0.05-0.68 kg/m2) (all P < 0.05). These changes were not observed in the control group (all P > 0.05). Notably, calf circumference decreased significantly in the control group (mean, -0.98 cm; 95% CI: -1.61 to -0.36 cm) but was maintained in the intervention group. The differences in the calf circumference and 6-m walk performance of the two groups were significant (P < 0.05).
CONCLUSIONS: The 12-week soy protein-rich meal intervention improved the muscle mass and 6-m walk performance of older adults in a long-term care facility.
METHODS: A 12-week single-center randomized controlled trial with a control-group and open-label design was conducted. Eighty-four older adults from a long-term care facility participated in the study. The chefs at the facility cooked three meals using soy protein-rich recipes designed by dieticians. For 12 weeks, the intervention group participants consumed three meals with 30 g of soy protein (10 g/meal) per day, and the control group participants maintained their habitual diets.
RESULTS: The 84 participants (mean age, 84.9 ± 7.0 years; 61.9% female) were randomly assigned to an intervention group (43 participants) and a control group (41 participants). The intervention group exhibited significant increases in several lean mass indicators, namely soft lean mass (mean, 1.43 kg; 95% confidence interval [CI]: 0.20-1.65 kg), skeletal muscle mass (mean, 1.20 kg; 95% CI: 0.43-1.96 kg), appendicular skeletal muscle mass (mean, 0.79 kg; 95% CI: 0.07-1.52 kg), and skeletal muscle index (mean, 0.37 kg/m2; 95% CI: 0.05-0.68 kg/m2) (all P < 0.05). These changes were not observed in the control group (all P > 0.05). Notably, calf circumference decreased significantly in the control group (mean, -0.98 cm; 95% CI: -1.61 to -0.36 cm) but was maintained in the intervention group. The differences in the calf circumference and 6-m walk performance of the two groups were significant (P < 0.05).
CONCLUSIONS: The 12-week soy protein-rich meal intervention improved the muscle mass and 6-m walk performance of older adults in a long-term care facility.
摘要：
目的：本研究调查了富含大豆蛋白的膳食干预对长期护理机构中老年人肌肉健康的影响。
方法：进行为期12周的单中心随机对照试验，对照组和开放标签设计。来自长期护理机构的84名老年人参加了这项研究。该设施的厨师使用营养师设计的富含大豆蛋白的食谱烹饪三餐。12周,干预组参与者每天吃三餐30克大豆蛋白(10克/餐)，对照组参与者保持他们的习惯性饮食。
结果：84名参与者(平均年龄，84.9±7.0岁；61.9％的女性）被随机分配到干预组（43名参与者）和对照组（41名参与者）。干预组的几个瘦体重指标显着增加，即软瘦质量(平均值，1.43千克；95%置信区间[CI]：0.20-1.65千克），骨骼肌质量(平均值，1.20千克；95%CI：0.43-1.96千克），阑尾骨骼肌质量(平均值，0.79千克；95%CI：0.07-1.52千克），和骨骼肌指数(平均值，0.37kg/m2;95%CI:0.05-0.68kg/m2(均P<0.05)。对照组未见上述变化(均P>0.05)。值得注意的是,对照组小腿围显着降低(平均值，-0.98cm；95％CI：-1.61至-0.36cm），但在干预组中保持不变。两组小腿围及6米步行表现差异有统计学意义(P<0.05)。
结论：在长期护理机构中，12周的富含大豆蛋白的膳食干预改善了老年人的肌肉质量和6米步行表现。
方法：进行为期12周的单中心随机对照试验，对照组和开放标签设计。来自长期护理机构的84名老年人参加了这项研究。该设施的厨师使用营养师设计的富含大豆蛋白的食谱烹饪三餐。12周,干预组参与者每天吃三餐30克大豆蛋白(10克/餐)，对照组参与者保持他们的习惯性饮食。
结果：84名参与者(平均年龄，84.9±7.0岁；61.9％的女性）被随机分配到干预组（43名参与者）和对照组（41名参与者）。干预组的几个瘦体重指标显着增加，即软瘦质量(平均值，1.43千克；95%置信区间[CI]：0.20-1.65千克），骨骼肌质量(平均值，1.20千克；95%CI：0.43-1.96千克），阑尾骨骼肌质量(平均值，0.79千克；95%CI：0.07-1.52千克），和骨骼肌指数(平均值，0.37kg/m2;95%CI:0.05-0.68kg/m2(均P<0.05)。对照组未见上述变化(均P>0.05)。值得注意的是,对照组小腿围显着降低(平均值，-0.98cm；95％CI：-1.61至-0.36cm），但在干预组中保持不变。两组小腿围及6米步行表现差异有统计学意义(P<0.05)。
结论：在长期护理机构中，12周的富含大豆蛋白的膳食干预改善了老年人的肌肉质量和6米步行表现。
