关键词: Association of spontaneous coronary dissection and takotsubo syndrome Pathophysiology of spontaneous coronary dissection Pathophysiology of takotsubo syndrome Spontaneous coronary dissection Takotsubo syndrome

Mesh : Takotsubo Cardiomyopathy / diagnosis physiopathology Humans Coronary Vessel Anomalies / diagnosis complications Vascular Diseases / diagnosis congenital Coronary Angiography / methods Coronary Vessels / diagnostic imaging

来  源:   DOI:10.1016/j.cpcardiol.2024.102744

Abstract:
There is ample literature revealing an association of SCAD with TTS, while it is not clear whether these 2 pathological entities are mechanistically linked in the sense that the one triggers the other. Considering that physical/emotional stress triggers TTS, it is plausible that stress related to SCAD, could result in the emergence of TTS. Conversely, it has been speculated that the junction between hypercontractile and akinetic/dyskinetic myocardium regions in TTS could lead to a \"hinge pivoting point\", imparting vascular disruption in coronary arteries, crossing these abutting myocardial planes, in susceptible individuals, causing SCAD.
摘要:
有大量文献揭示了SCAD与TTS的关联,虽然目前尚不清楚这2个病理实体是否在机制上联系在一起,因为一个触发了另一个。考虑到身体/情绪压力会触发TTS,与SCAD有关的压力似乎是合理的,可能导致TTS的出现。相反,据推测,TTS中过度收缩和运动/运动障碍心肌区域之间的交界处可能导致“铰链枢转点”,赋予冠状动脉血管破裂,穿过这些邻接的心肌平面,在易感个体中,导致SCAD。
公众号