Abstract：
The aim of this study was to assess test-retest reliability and diagnostic validity of self-report instruments of depression and anxiety in autistic youth. Participants were 55 autistic youth aged 8-17 years presenting with depressive or anxiety symptoms. They were interviewed with the Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children (K-SADS-PL) and completed the Children\'s Depression Inventory, Second Edition - Self Report Short (CDI 2:SR[S]) and the Revised Child Anxiety and Depression Scale (RCADS) twice, separated by a two-week interval. Test-retest reliability was measured with intraclass correlation coefficients (ICCs), and diagnostic validity was assessed using receiver operating characteristic (ROC) curves with the summary ratings on the K-SADS-PL as the criterion. The effect of participant characteristics was analyzed through a moderation analysis. Generalized anxiety (GAD) and social anxiety disorder (SOC) were the two most prevalent disorders in the sample. Test-retest reliability for most of the subscales was good (ICC = 0.74 - 0.87), with the exception of the RCADS obsessive-compulsive disorder (OCD) and GAD. The Adaptive Behavior conceptual score was a significant moderator of the reliability of the CDI 2:SR[S]. The ROC analysis suggested the RCADS SOC and the CDI 2:SR[S] to be good screening tools with inadequate specificity when appropriately sensitive cutoff scores are used. Optimal cutoff scores in this sample were lower than originally published. The findings suggest that autistic youth can provide stable reports of anxiety and depressive symptoms over time. Diagnostic validity varied according to the construct and instrument.
摘要：
这项研究的目的是评估自闭症青年抑郁和焦虑自我报告工具的重测信度和诊断效度。参与者是55名8-17岁的自闭症青年，表现出抑郁或焦虑症状。他们接受了学龄儿童情感障碍和精神分裂症Kiddie时间表（K-SADS-PL）的采访，并完成了儿童抑郁量表，第二版-自我报告简短（CDI2：SR[S]）和修订的儿童焦虑和抑郁量表（RCADS）两次，间隔两周。重测可靠性用类内相关系数(ICC)测量，并使用受试者工作特征（ROC）曲线评估诊断有效性，以K-SADS-PL的摘要等级为标准。通过适度分析对参与者特征的影响进行了分析。广泛性焦虑（GAD）和社交焦虑症（SOC）是样本中最常见的两种疾病。大多数子量表的重测信度良好(ICC=0.74-0.87)，除了RCADS强迫症（OCD）和GAD。适应性行为概念评分是CDI2：SR[S]可靠性的重要调节因素。ROC分析表明，当使用适当敏感的截止分数时，RCADSSOC和CDI2：SR[S]是特异性不足的良好筛选工具。该样本中的最佳截止分数低于最初公布的分数。研究结果表明，随着时间的推移，自闭症青年可以提供稳定的焦虑和抑郁症状报告。诊断有效性因结构和仪器而异。
