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Abstract：
BACKGROUND: Appropriate cut-off values and diagnostic accuracy (DA) [sensitivity, specificity, predictive values, positive (PPV) and negative (NPV)] of electrodiagnostic findings for carpal tunnel syndrome (CTS) based on age, gender, and diabetes mellitus (DM) were not reported.
METHODS: In a retrospective study, we described the latency difference values and DA of comparative latency studies COLS [median to ulnar through palmar difference (palmdiff) and ring difference study (ringdiff), median to radial through thumb difference study (thumbdiff), and combined sensory index (CSI)] among non-CTS and CTS groups based on age, DM, and gender.
RESULTS: We included 632 patients (228 without CTS and 404 with CTS). For PPV > 90% and NPV > 50%, the best cut-offs among patients without DM, were 0.5ms, 0.8-1 ms, 1.4 ms, and 2 ms for palmdiff, thumbdiff, CSI (age < 60 years), and CSI (age > 60 years), respectively. The best cut-offs among patients with DM were 0.5 ms, 1.2 ms, 0.8 ms, 1.0-1.2 ms, 1.8 ms, 1-1.2 ms, 3.0 ms, and 3.5 ms for palmdiff (age < 50 years), palmdiff (age > 50 years), thumbdiff (age < 40 years), thumbdiff (age 40-59 years), thumbdiff (age > 60 years), CSI (age < 50 years), CSI (age 50-59 years), and CSI (age > 60 years), respectively.
CONCLUSIONS: The cut-off values of COLS to confirm CTS and their DA were different according to age and DM.
METHODS: In a retrospective study, we described the latency difference values and DA of comparative latency studies COLS [median to ulnar through palmar difference (palmdiff) and ring difference study (ringdiff), median to radial through thumb difference study (thumbdiff), and combined sensory index (CSI)] among non-CTS and CTS groups based on age, DM, and gender.
RESULTS: We included 632 patients (228 without CTS and 404 with CTS). For PPV > 90% and NPV > 50%, the best cut-offs among patients without DM, were 0.5ms, 0.8-1 ms, 1.4 ms, and 2 ms for palmdiff, thumbdiff, CSI (age < 60 years), and CSI (age > 60 years), respectively. The best cut-offs among patients with DM were 0.5 ms, 1.2 ms, 0.8 ms, 1.0-1.2 ms, 1.8 ms, 1-1.2 ms, 3.0 ms, and 3.5 ms for palmdiff (age < 50 years), palmdiff (age > 50 years), thumbdiff (age < 40 years), thumbdiff (age 40-59 years), thumbdiff (age > 60 years), CSI (age < 50 years), CSI (age 50-59 years), and CSI (age > 60 years), respectively.
CONCLUSIONS: The cut-off values of COLS to confirm CTS and their DA were different according to age and DM.
摘要：
背景：适当的截止值和诊断准确性（DA）[灵敏度，特异性，预测值，基于年龄的腕管综合征（CTS）的电诊断结果为阳性（PPV）和阴性（NPV）]，性别,和糖尿病（DM）未报告。
方法：在一项回顾性研究中，我们描述了比较潜伏期研究COLS的潜伏期差异值和DA[通过掌间差异（palmdiff）和环差异研究（ringdiff），通过拇指差异研究(拇指差异)，基于年龄的非CTS和CTS组的组合感觉指数(CSI)]，DM,和性别。
结果：我们纳入了632例患者（228例无CTS，404例有CTS）。对于PPV>90%和NPV>50%，在没有DM的患者中最好的截止点，是0.5ms，0.8-1ms,1.4ms,和2毫秒的palmdiff，thumbdiff,CSI（年龄<60岁），和CSI（年龄>60岁），分别。DM患者的最佳截止时间为0.5ms，1.2ms,0.8ms,1.0-1.2ms,1.8ms,1-1.2ms,3.0ms,palmdiff（年龄<50岁）为3.5ms，palmdiff（年龄>50岁），thumbdiff（年龄<40岁），thumbdiff（年龄40-59岁），thumbdiff（年龄>60岁），CSI（年龄<50岁），CSI（年龄50-59岁），和CSI（年龄>60岁），分别。
结论：根据年龄和DM，确定CTS的COLS及其DA的临界值不同。
方法：在一项回顾性研究中，我们描述了比较潜伏期研究COLS的潜伏期差异值和DA[通过掌间差异（palmdiff）和环差异研究（ringdiff），通过拇指差异研究(拇指差异)，基于年龄的非CTS和CTS组的组合感觉指数(CSI)]，DM,和性别。
结果：我们纳入了632例患者（228例无CTS，404例有CTS）。对于PPV>90%和NPV>50%，在没有DM的患者中最好的截止点，是0.5ms，0.8-1ms,1.4ms,和2毫秒的palmdiff，thumbdiff,CSI（年龄<60岁），和CSI（年龄>60岁），分别。DM患者的最佳截止时间为0.5ms，1.2ms,0.8ms,1.0-1.2ms,1.8ms,1-1.2ms,3.0ms,palmdiff（年龄<50岁）为3.5ms，palmdiff（年龄>50岁），thumbdiff（年龄<40岁），thumbdiff（年龄40-59岁），thumbdiff（年龄>60岁），CSI（年龄<50岁），CSI（年龄50-59岁），和CSI（年龄>60岁），分别。
结论：根据年龄和DM，确定CTS的COLS及其DA的临界值不同。
