核碱基和烟酰胺代谢的双重作用的结构 - 功能见解以及 URH1 β 核苷水解酶在癌症基因治疗中的可能用途。
关键词: NAD+ X-ray crystallography cancer therapy enzymology metabolism nucleosides
Mesh : Niacinamide / analogs & derivatives metabolism chemistry Saccharomyces cerevisiae / genetics metabolism Saccharomyces cerevisiae Proteins / metabolism genetics chemistry Neoplasms / drug therapy genetics metabolism Structure-Activity Relationship Pyridinium Compounds / metabolism chemistry N-Glycosyl Hydrolases / metabolism genetics chemistry Uridine / metabolism analogs & derivatives chemistry Substrate Specificity Humans Models, Molecular
来 源:
DOI:10.3390/ijms25137032
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