PDF(Pubmed)
Abstract：
There is currently little research on the effects of reduced left ventricular ejection fraction and altered nutritional status in patients with acute myocardial infarction. We therefore examined the interrelationship between the parameters of left ventricular dysfunction after acute myocardial infarction and changes in the Geriatric Nutrition Risk Index (GNRI) and the Nutrition Status Control Index (CONUT). Based on the evidence, frailty is considered to be an important factor affecting the prognosis of cardiovascular disease, so it is important to detect malnutrition early to prevent adverse cardiovascular events. This study was an observational, prospective study that included a total of 73 subjects who presented at the 3-month AMI follow-up. All subjects were subjected to laboratory tests and the groups were divided as follows: group 1, in which we calculated the CONUT score, (CONUT < 3 points, n = 57) patients with normal nutritional status and patients with moderate to severe nutritional deficiency (CONUT ≥ 3, n = 16). In group 2, the GNRI score was calculated and out of the 73 patients we had: GNRI ≥ 98, n = 50, patients with normal nutritional status, and GNRI < 98, n = 23, patients with altered nutritional status. The results of this study showed that we had significant differences between LVEF values at 3 months post-infarction where, in the CONUT group, patients with altered nutritional status had lower LVEF values (46.63 ± 3.27% versus 42.94 ± 2.54%, p < 0.001) compared to CONUT < 3. Also, in the GNRI group, we had lower LVEF values in patients with impaired nutritional status (46.48 ± 3.35% versus 44.39 ± 3.35%, p = 0.01). It can be seen that LVEF values are improved at 3 months post infarction in both groups, in patients with impaired nutritional status and in patients with good nutritional status. Patients with impaired nutritional status have lower ejection fraction and worse outcomes in both the CONUT and GNRI groups at 3 months post acute myocardial infarction.
摘要：
目前，关于急性心肌梗死患者左心室射血分数降低和营养状况改变的影响的研究很少。因此，我们研究了急性心肌梗死后左心室功能障碍参数与老年营养风险指数（GNRI）和营养状况控制指数（CONUT）变化之间的相互关系。根据证据,衰弱被认为是影响心血管疾病预后的重要因素,因此，早期发现营养不良对预防不良心血管事件非常重要。这项研究是一项观察性的，前瞻性研究包括在3个月AMI随访中出现的总共73名受试者。所有受试者都接受了实验室测试，分组如下：第1组，我们计算了CONUT评分，(CONUT<3分,n=57）营养状态正常的患者和中度至重度营养缺乏的患者（CONUT≥3，n=16）。在第2组中，计算了GNRI评分，在我们拥有的73例患者中：GNRI≥98，n=50，营养状况正常的患者，GNRI<98，n=23，营养状况改变的患者。这项研究的结果表明，我们在梗死后3个月的LVEF值之间存在显着差异，在CONUT组中，营养状况改变的患者LVEF值较低(46.63±3.27%vs42.94±2.54%,p<0.001)与CONUT<3相比。此外，在GNRI组中，在营养状态受损的患者中，我们的LVEF值较低（46.48±3.35％与44.39±3.35％，p=0.01)。可以看出，两组在梗死后3个月LVEF值均有改善，营养状况受损的患者和营养状况良好的患者。营养状态受损的患者在急性心肌梗死后3个月时，CONUT和GNRI组的射血分数较低，预后较差。
