PDF(Pubmed)
Abstract：
(1) Background: Asthma is a syndrome found in both adults and children, characterized by airflow obstruction caused by the inflammation of the airways. In recent years, an increasing number of studies have found that lipid metabolism influences both the development and symptomatology of asthma. Lipid metabolism plays an important role both in the occurrence of exacerbations and in the reduction of lung inflammation. Our study aimed to identify any type of association between patients diagnosed with asthma and their serum lipids, including HDL-cholesterol, LDL-cholesterol, total cholesterol, and triglycerides in adults. (2) Methods: To find articles for our review, we searched two platforms: PubMed and Google Scholar. A total of 309 articles from two platforms were analyzed. Finally, 12 papers were selected from the initial pool of identified articles. (3) Results: The positive correlation between triglycerides, total cholesterol, low-density lipoprotein-cholesterol (LDL-cholesterol), and asthma has been demonstrated in several studies. Moreover, it appears that there is an association between biomarkers of type 2 inflammation and HDL and serum triglycerides in people with atopic status. Regarding the nutrition of asthmatic patients, the greatest impact on the development of the disease seems to be the consumption of fruit and vegetables. Several studies show that a predominantly vegan diet is associated with better control of the disease and a decrease in the number of pro-inflammatory cytokines. (4) Conclusions: Studies show a positive correlation between total cholesterol, triglyceride, and LDL-cholesterol levels and asthma and a negative correlation between HDL-cholesterol and asthma. Increased cholesterol values would lead to the stimulation of pro-inflammatory processes and the secretion of cytokines involved in these processes. The most successful diets for asthma patients seem to be those in which the consumption of fruit, vegetables, and high-fiber foods is increased because all of these food groups are rich in vitamins, antioxidants, and minerals.
摘要：
（1）背景：哮喘是一种在成人和儿童中发现的综合征，以气道炎症引起的气流阻塞为特征。近年来,越来越多的研究发现，脂质代谢影响哮喘的发展和症状学。脂质代谢在加重的发生和减轻肺部炎症中起重要作用。我们的研究旨在确定诊断为哮喘的患者与血脂之间的任何类型的关联，包括HDL-胆固醇,LDL-胆固醇,总胆固醇,和成人的甘油三酯。（2）方法：找到供我们评论的文章，我们搜索了两个平台：PubMed和GoogleScholar。共分析了来自两个平台的309篇文章。最后,从最初的已识别文章库中选择了12篇论文。(3)结果:甘油三酯之间呈正相关,总胆固醇,低密度脂蛋白胆固醇（LDL-胆固醇），哮喘已在多项研究中得到证实。此外，在特应性患者中,2型炎症的生物标志物与HDL和血清甘油三酯之间似乎存在关联.关于哮喘患者的营养，对疾病发展的最大影响似乎是水果和蔬菜的消费。一些研究表明，以素食为主的饮食与更好地控制疾病和减少促炎细胞因子的数量有关。(4)结论:研究表明总胆固醇与胆固醇呈正相关,甘油三酯，LDL-胆固醇水平与哮喘呈负相关，HDL-胆固醇与哮喘呈负相关。增加的胆固醇值将导致促炎过程的刺激和参与这些过程的细胞因子的分泌。哮喘患者最成功的饮食似乎是那些食用水果的饮食，蔬菜,高纤维食物增加是因为所有这些食物都富含维生素，抗氧化剂,和矿物。
