关键词: autografting autologous autotransplantation bone regeneration growth factor plasma platelet-rich fibrin

来  源:   DOI:10.3390/jcm13133902   PDF(Pubmed)

Abstract:
Background: Tooth infraocclusion is a process in which a completely or partially erupted tooth gradually moves away from the occlusal plane. Submerged teeth can lead to serious complications. Treating teeth with infraocclusion is very challenging. One of the procedures allowing for the replacement of a missing tooth is autotransplantation. The aim of this paper is to review the literature on teeth autotransplantation, supported by a case report involving the autotransplantation of a third mandibular molar into the site of an extracted infraoccluded first mandibular molar, as well as the utilization of advanced platelet-rich fibrin (A-PRF) alongside autogenous dentin grafts for bone tissue regeneration. Methods: A severely infraoccluded first permanent right mandibular molar was extracted and then ground to obtain the dentin graft. A-PRF clots (collected from the patient\'s peripheral blood) were added to the autogenous dentin graft, to create the A-PRF membrane. An atraumatic extraction of the lower left third molar was performed and then it was transplanted into the socket of tooth no. 46. Immediately after transplantation, tooth no. 38 was stabilized with orthodontic bracket splints for 3 months. The patient attended regular follow-up visits within 12 months. Results: After one year, the patient did not report any pain. In the clinical examination, the tooth and surrounding tissues did not show any signs of infection. However, radiographically, cervical inflammatory resorption, unchanged pulp canal dimensions, absent root growth, periapical radiolucency, and lack of apical and marginal healing were observed. Reconstruction of the bone defect was obtained and the alveolar ridge of the mandible was preserved. Due to poor stability of the tooth and severe resorption, the tooth needed to be extracted. Conclusions: This study is designed to critically evaluate the efficacy of autotransplantation, the application of growth factors, and the integration of autogenous dentin grafts in remedying dental deficiencies resulting from reinclusion. We aim to point out the possible causes of treatment failure.
摘要:
背景:牙内闭塞是完全或部分萌出的牙齿逐渐远离咬合平面的过程。浸没的牙齿可导致严重的并发症。治疗牙内咬合是非常具有挑战性的。允许更换缺失牙齿的方法之一是自体移植。本文的目的是回顾有关牙齿自体移植的文献,得到了一个病例报告的支持,该病例报告涉及将第三下颌磨牙自体移植到被拔出的第一下颌磨牙的位置,以及利用先进的富血小板纤维蛋白(A-PRF)和自体牙本质移植物进行骨组织再生。方法:拔除严重闭塞的第一永久性右下颌磨牙,然后进行研磨以获得牙本质移植物。将A-PRF凝块(从患者外周血中收集)添加到自体牙本质移植物中,来制造A-PRF膜。对左下第三磨牙进行了无创伤拔除,然后将其移植到牙槽中。46.移植后立即,牙号用正畸托槽夹板固定38个月。患者在12个月内进行定期随访。结果:一年后,患者没有报告任何疼痛。在临床检查中,牙齿和周围组织没有任何感染迹象。然而,射线照相,宫颈炎症吸收,牙髓管尺寸不变,根没有生长,根尖周射线可透性,并观察到根尖和边缘愈合的缺乏。获得了骨缺损的重建,并保留了下颌骨的牙槽脊。由于牙齿的稳定性差和严重的再吸收,牙齿需要拔掉。结论:本研究旨在严格评估自体移植的疗效,生长因子的应用,以及自体牙本质移植物的整合,以弥补因重新纳入而导致的牙齿缺陷。我们旨在指出治疗失败的可能原因。
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