新型偏向性 Mu 阿片受体激动剂的合成及生物学评价.
关键词: PZM21 safer opioids structure activity relationship µOR-biased agonist β-arrestin-2 recruitment
Mesh : Receptors, Opioid, mu / agonists metabolism Animals Mice Molecular Docking Simulation Analgesics, Opioid / pharmacology chemistry chemical synthesis Humans Structure-Activity Relationship Pain / drug therapy Male Molecular Structure Thiophenes Urea / analogs & derivatives
来 源:
DOI:10.3390/molecules29132961
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