关键词: anodizing biomaterials cell attachment corrosion rate

来  源:   DOI:10.3390/ma17133347   PDF(Pubmed)

Abstract:
This paper reports on the coating of heterostructured TiO2 nanopores/nanotubes on Ti substrates by anodizing at high voltages to design surfaces for biomedical implants. As the anodized voltage from 50 V to 350 V was applied, the microstructure of the coating shifted from regular TiO2 nanotubes to heterostructured TiO2 nanopores/nanotubes. In addition, the dimension of the heterostructured TiO2 nanopores/nanotubes was a function of voltage. The electrochemical characteristics of TiO2 nanotubes and heterostructured TiO2 nanopores/nanotubes were evaluated in simulated body fluid (SBF) solution. The creation of heterostructured TiO2 nanopores/nanotubes on Ti substrates resulted in a significant increase in BHK cell attachment compared to that of the Ti substrates and the TiO2 nanotubes.
摘要:
本文报道了通过在高电压下阳极氧化在Ti基底上涂覆异质结构的TiO2纳米孔/纳米管,以设计生物医学植入物的表面。当施加50V至350V的阳极化电压时,涂层的微观结构从规则的TiO2纳米管转变为异质结构的TiO2纳米孔/纳米管。此外,异质结构TiO2纳米孔/纳米管的尺寸是电压的函数。在模拟体液(SBF)溶液中评估了TiO2纳米管和异质结构TiO2纳米孔/纳米管的电化学特性。与Ti基底和TiO2纳米管相比,在Ti基底上产生异质结构的TiO2纳米孔/纳米管导致BHK细胞附着显着增加。
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