METHODS: Patients aged ≥16 years enrolled in JIPAD between April 2015 and March 2018 after surgical brain tumor resection or biopsy of brain tumors. We examined factors related to outcomes at discharge based on blood tests and medical procedures performed during ICU admission, tumor type, and APACHE II score.
RESULTS: Among the 1454 patients (male:female ratio: 1:1.1, mean age: 62 years) in the study, 32 (2.2 %) died during hospital stay. In multivariate analysis, male sex (odds ratio [OR] 2.70, [95 % confidence interval, CI 1.22-6.00]), malignant tumor (OR 2.51 [95 % CI 1.13-5.55]), and APACHE II score ≥15 (OR 2.51 [95 % CI 3.08-14.3]) were significantly associated with in-hospital mortality.
CONCLUSIONS: By picking up cases with a high risk of in-hospital death at an early stage, it is possible to improve methods of treatment and support for the patient\'s family.
方法:2015年4月至2018年3月,在脑肿瘤手术切除或脑肿瘤活检后,年龄≥16岁的患者纳入JIPAD。我们根据血液检查和ICU入住期间的医疗程序检查了与出院时结果相关的因素,肿瘤类型,和APACHEII得分。
结果:在研究中的1454名患者中(男性:女性比例:1:1.1,平均年龄:62岁),32人(2.2%)在住院期间死亡。在多变量分析中,男性(优势比[OR]2.70,[95%置信区间,CI1.22-6.00]),恶性肿瘤(OR2.51[95%CI1.13-5.55]),APACHEII评分≥15(OR2.51[95%CI3.08-14.3])与住院死亡率显著相关.
结论:通过在早期发现院内死亡风险较高的病例,改善治疗方法和对患者家属的支持是可能的。