Mesh : Humans Intracranial Aneurysm / epidemiology pathology complications Aneurysm, Ruptured Male Female Middle Aged Risk Factors Aged Retrospective Studies Adult Age Factors Carotid Artery, Internal / pathology Logistic Models

来  源:   DOI:10.1097/MD.0000000000038909   PDF(Pubmed)

Abstract:
To compare the differences in clinical and morphological features between small ruptured intracranial aneurysms and large unruptured intracranial aneurysms to evaluate the risk factors for the rupture of IAs. The clinical data of 189 consecutive patients with 193 IAs were reviewed. The patients and IAs were divided into ruptured (<5 mm) and unruptured groups (>10 mm). The characteristics of the patients and the intracranial aneurysms (IAs) were compared between the 2 groups, and the risk factors for rupture of IAs were assessed using multiple logistic regression. Patient age (odds ratio [OR], 0.955), IA located at the internal carotid artery (ICA, OR, 0.202), irregular shape (OR, 0.083) and parent vessel diameter (OR, 0.426) were negatively correlated with the risk of IA rupture. IAs located at bifurcations (OR, 6.766) were positively correlated with the risk of IA rupture. In addition to the size of the IAs, regardless of IAs shape, other factors, such as younger age (<63.5 years), location at a bifurcation, IAs located at the ICA and a small parent vessel diameter (<3.25 mm), can influence the risk of IA rupture.
摘要:
比较颅内破裂小动脉瘤与颅内未破裂大动脉瘤在临床和形态学特征上的差异,以评估IAs破裂的危险因素。回顾了189例连续患者193例IAs的临床资料。将患者和IAs分为破裂组(<5mm)和未破裂组(>10mm)。比较两组患者的特点及颅内动脉瘤(IAs),采用多元logistic回归分析评估IAs破裂的危险因素。患者年龄(比值比[OR],0.955),IA位于颈内动脉(ICA,OR,0.202),不规则形状(或,0.083)和母血管直径(OR,0.426)与IA破裂风险呈负相关。位于分叉处的IAs(或,6.766)与IA破裂风险呈正相关。除了IAs的大小之外,无论IAs的形状如何,其他因素,例如年龄较小(<63.5岁),在分叉处的位置,IAs位于ICA和小的父血管直径(<3.25mm),会影响IA破裂的风险。
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