PDF(Pubmed)
Abstract：
BACKGROUND: Cholera outbreaks in Ethiopia necessitate frequent mass oral cholera vaccine (OCV) campaigns. Despite this, there is a notable absence of a comprehensive summary of these campaigns. Understanding national OCV vaccination history is essential to design appropriate and effective cholera control strategies. Here, we aimed to retrospectively review all OCV vaccination campaigns conducted across Ethiopia between 2019 and 2023.
METHODS: The OCV request records from 2019 to October 2023 and vaccination campaign reports for the period from 2019 to December 2023 were retrospectively accessed from the Ethiopia Public Health Institute (EPHI) database. Descriptive analysis was conducted using the retrospective data collected.
RESULTS: From 2019 to October 2023, Ethiopian government requested 32 044 576 OCV doses (31 899 576 doses to global stockpile; 145 000 doses to outside of stockpile). Around 66.3% of requested doses were approved; of which 90.4% were received. Fifteen OCV campaigns (12 reactive and 3 pre-emptive) were conducted, including five two-dose campaigns with varying dose intervals and single-dose campaigns partially in 2019 and entirely in 2021, 2022 and 2023. Overall vaccine administrative coverage was high; except for Tigray region (41.8% in the 1st round; 2nd round didn\'t occur). The vaccine administrative coverage records were documented, but no OCV coverage survey data was available.
CONCLUSIONS: This study represents the first comprehensive review of OCV campaigns in Ethiopia spanning the last five years. Its findings offer valuable insights into informing future cholera control strategies, underscoring the importance of monitoring and evaluation despite resource constraints. Addressing the limitations in coverage survey data availability is crucial for enhancing the efficacy of future campaigns.
METHODS: The OCV request records from 2019 to October 2023 and vaccination campaign reports for the period from 2019 to December 2023 were retrospectively accessed from the Ethiopia Public Health Institute (EPHI) database. Descriptive analysis was conducted using the retrospective data collected.
RESULTS: From 2019 to October 2023, Ethiopian government requested 32 044 576 OCV doses (31 899 576 doses to global stockpile; 145 000 doses to outside of stockpile). Around 66.3% of requested doses were approved; of which 90.4% were received. Fifteen OCV campaigns (12 reactive and 3 pre-emptive) were conducted, including five two-dose campaigns with varying dose intervals and single-dose campaigns partially in 2019 and entirely in 2021, 2022 and 2023. Overall vaccine administrative coverage was high; except for Tigray region (41.8% in the 1st round; 2nd round didn\'t occur). The vaccine administrative coverage records were documented, but no OCV coverage survey data was available.
CONCLUSIONS: This study represents the first comprehensive review of OCV campaigns in Ethiopia spanning the last five years. Its findings offer valuable insights into informing future cholera control strategies, underscoring the importance of monitoring and evaluation despite resource constraints. Addressing the limitations in coverage survey data availability is crucial for enhancing the efficacy of future campaigns.
摘要：
背景：埃塞俄比亚的霍乱暴发需要频繁的大规模口服霍乱疫苗（OCV）活动。尽管如此,明显缺乏对这些运动的全面总结。了解国家OCV疫苗接种历史对于设计适当和有效的霍乱控制策略至关重要。这里,我们旨在回顾性审查2019年至2023年在埃塞俄比亚开展的所有OCV疫苗接种活动.
方法：从埃塞俄比亚公共卫生研究所（EPHI）数据库回顾性访问了2019年至2023年10月的OCV请求记录和2019年至2023年12月的疫苗接种活动报告。使用收集的回顾性数据进行描述性分析。
结果：从2019年到2023年10月，埃塞俄比亚政府要求32044576OCV剂量（全球库存31899576剂；库存外145000剂）。大约66.3%的请求剂量被批准;其中90.4%被接收。进行了15次OCV运动(12次反应性运动和3次先发制人)，包括五个剂量间隔不同的两剂量运动和单剂量运动，部分在2019年和全部在2021年，2022年和2023年。总体疫苗管理覆盖率较高；除Tigray地区外（第一轮为41.8％；第二轮未发生）。疫苗管理覆盖记录已记录在案，但没有OCV覆盖率调查数据.
结论：这项研究是对埃塞俄比亚近5年OCV运动的第一次全面回顾。它的发现为未来的霍乱控制策略提供了有价值的见解，强调尽管资源有限，但监测和评估的重要性。解决覆盖范围调查数据可用性的局限性对于提高未来运动的效力至关重要。
方法：从埃塞俄比亚公共卫生研究所（EPHI）数据库回顾性访问了2019年至2023年10月的OCV请求记录和2019年至2023年12月的疫苗接种活动报告。使用收集的回顾性数据进行描述性分析。
结果：从2019年到2023年10月，埃塞俄比亚政府要求32044576OCV剂量（全球库存31899576剂；库存外145000剂）。大约66.3%的请求剂量被批准;其中90.4%被接收。进行了15次OCV运动(12次反应性运动和3次先发制人)，包括五个剂量间隔不同的两剂量运动和单剂量运动，部分在2019年和全部在2021年，2022年和2023年。总体疫苗管理覆盖率较高；除Tigray地区外（第一轮为41.8％；第二轮未发生）。疫苗管理覆盖记录已记录在案，但没有OCV覆盖率调查数据.
结论：这项研究是对埃塞俄比亚近5年OCV运动的第一次全面回顾。它的发现为未来的霍乱控制策略提供了有价值的见解，强调尽管资源有限，但监测和评估的重要性。解决覆盖范围调查数据可用性的局限性对于提高未来运动的效力至关重要。
