PDF(Pubmed)
Abstract：
UNASSIGNED: A picture naming test is presented that reveals impairment to specific mechanisms involved in the naming process, using accuracy scores on curated item sets. A series of psychometric validation experiments are reported.
UNASSIGNED: Using a computational model that enables estimation of item difficulty at the lexical and sublexical stages of word retrieval, two complimentary sets of items were constructed that challenge the respective psycholinguistic levels of representation. The difference in accuracy between these item sets yields the relative linguistic impairment (RLI) score. In a cohort of 91 people with chronic left-hemisphere stroke who enrolled in a clinical trial for anomia, we assessed psychometric properties of the RLI score and then used the new scale to make predictions about other language behaviors, lesion distributions, and functional activation during naming.
UNASSIGNED: RLI scores had adequate psychometric properties for clinical significance. RLI scores contained predictive information about spontaneous speech fluency, over and above accuracy. A dissociation was observed between performance on the RLI item sets and performance on the subtests of an independent language battery. Sublexical RLI was significantly associated with apraxia of speech and with lesions encompassing perisylvian regions, while lexical RLI was associated with lesions to deep white matter. The RLI construct was reflected in functional brain activity during naming, independent of overall accuracy, with a respective shift of activation between dorsal and ventral networks responsible for different aspects of word retrieval.
UNASSIGNED: The RLI assessment satisfies the psychometric requirements to serve as a useful clinical measure.
UNASSIGNED: Using a computational model that enables estimation of item difficulty at the lexical and sublexical stages of word retrieval, two complimentary sets of items were constructed that challenge the respective psycholinguistic levels of representation. The difference in accuracy between these item sets yields the relative linguistic impairment (RLI) score. In a cohort of 91 people with chronic left-hemisphere stroke who enrolled in a clinical trial for anomia, we assessed psychometric properties of the RLI score and then used the new scale to make predictions about other language behaviors, lesion distributions, and functional activation during naming.
UNASSIGNED: RLI scores had adequate psychometric properties for clinical significance. RLI scores contained predictive information about spontaneous speech fluency, over and above accuracy. A dissociation was observed between performance on the RLI item sets and performance on the subtests of an independent language battery. Sublexical RLI was significantly associated with apraxia of speech and with lesions encompassing perisylvian regions, while lexical RLI was associated with lesions to deep white matter. The RLI construct was reflected in functional brain activity during naming, independent of overall accuracy, with a respective shift of activation between dorsal and ventral networks responsible for different aspects of word retrieval.
UNASSIGNED: The RLI assessment satisfies the psychometric requirements to serve as a useful clinical measure.
摘要：
■提出了一种图片命名测试，该测试揭示了命名过程中涉及的特定机制的损害，在策划的项目集上使用准确性分数。报告了一系列心理测量验证实验。
■使用计算模型，可以在单词检索的词法和副词法阶段估计项目难度，构建了两套免费项目，挑战了各自的心理语言水平。这些项目集之间的准确性差异产生相对语言障碍（RLI）得分。在一组91名患有慢性左半球中风的人中，他们参加了一项关于失范的临床试验，我们评估了RLI分数的心理测量特性，然后使用新的量表来预测其他语言行为，病变分布，和命名过程中的功能激活。
■RLI评分具有足够的心理测量特性，具有临床意义。RLI分数包含有关自发言语流畅性的预测信息，超过精度。在RLI项目集的性能与独立语言电池的子测试的性能之间观察到分离。亚音RLI与言语失用症和周围的病变显着相关。而词汇RLI与深部白质病变有关。RLI构建体在命名过程中反映在功能性大脑活动中，独立于整体精度，在负责单词检索的不同方面的背侧和腹侧网络之间分别发生激活转移。
■RLI评估满足心理测量要求，可用作有用的临床测量。
■使用计算模型，可以在单词检索的词法和副词法阶段估计项目难度，构建了两套免费项目，挑战了各自的心理语言水平。这些项目集之间的准确性差异产生相对语言障碍（RLI）得分。在一组91名患有慢性左半球中风的人中，他们参加了一项关于失范的临床试验，我们评估了RLI分数的心理测量特性，然后使用新的量表来预测其他语言行为，病变分布，和命名过程中的功能激活。
■RLI评分具有足够的心理测量特性，具有临床意义。RLI分数包含有关自发言语流畅性的预测信息，超过精度。在RLI项目集的性能与独立语言电池的子测试的性能之间观察到分离。亚音RLI与言语失用症和周围的病变显着相关。而词汇RLI与深部白质病变有关。RLI构建体在命名过程中反映在功能性大脑活动中，独立于整体精度，在负责单词检索的不同方面的背侧和腹侧网络之间分别发生激活转移。
■RLI评估满足心理测量要求，可用作有用的临床测量。
