UNASSIGNED: This research aimed to evaluate the changes in the frequencies of micronucleated cells in patients\' buccal epithelial cells following dental panoramic radiography.
UNASSIGNED: 74 patients were recruited for the study who were advised for panoramic radiographs. Using a wooden spatula, the buccal epithelial cells were scraped from both cheeks before to panoramic radiation exposure and ten days after the panoramic radiation exposure. Giemsa stain was used to stain the cells, and 500 cells were scored on a slide to determine the frequency of micronuclei. To determine the difference between the frequency of micronuclei before and after radiation exposure, a paired t-test was used in the statistical analysis.
UNASSIGNED: The proportion of micronuclei cells was 0.11% before radiation exposure and 0.57% following radiation exposure after 10 days. A statistically significant increase in the frequencies of micronuclei was noted after radiation exposure values.
UNASSIGNED: This study revealed the genotoxicity of epithelial cells with dental panoramic radiation exposure. It is advised to reduce the use of such radiographs and to use only when there is no other diagnostic tool that is helpful or when absolutely essential.
■这项研究旨在评估牙科全景射线照相后患者口腔上皮细胞微核细胞频率的变化。
■本研究招募了74名患者,他们被建议进行全景X线摄影。用木铲,在全景辐射暴露前和全景辐射暴露后10天,从双颊刮去颊上皮细胞。Giemsa染色用于染色细胞,在载玻片上对500个细胞进行评分以确定微核的频率。为了确定辐射暴露前后微核频率的差异,统计学分析采用配对t检验.
■微核细胞的比例在辐射暴露前为0.11%,在辐射暴露10天后为0.57%。辐射暴露值后,发现微核频率在统计学上显着增加。
■这项研究揭示了牙齿全景辐射暴露对上皮细胞的遗传毒性。建议减少此类射线照片的使用,并且仅在没有其他有用的诊断工具或绝对必要时使用。