Abstract：
While low back pain (LBP) may persist or recur over time, few studies have evaluated the individual course of LBP over a long-term period, particularly among older adults. Based on data from the longitudinal Osteoporotic Fractures in Men (MrOS) study, we aimed to identify and describe different LBP trajectories in older men and characterize members in each trajectory group. A total of 5,976 community-dwelling men (mean age=74.2) enrolled at six US sites were analyzed. Participants self-reported LBP (yes/no) every 4 months during a maximum of 10 years. Latent class growth modelling was performed to identify unique LBP trajectory groups that explained variation in the LBP data. The association of baseline characteristics with trajectory group membership was assessed using univariable and multivariable multinominal logistic regression. A five-class solution was chosen; no/rare LBP (n=2442/40.9%), low frequency-stable LBP (n=1040/17.4%), low frequency-increasing LBP (n=719/12%), moderate frequency-decreasing LBP (n=745/12.5%) and high frequency-stable LBP (n=1030/17.2%). History of falls (OR=1.52), history of LBP (OR=6.37), higher physical impairment (OR=1.51-2.85) and worse psychological function (OR=1.41-1.62) at baseline were all associated with worse LBP trajectory groups in this sample of older men. These findings present an opportunity for targeted interventions and/or management to older men with worse or increasing LBP trajectories and associated modifiable risk factors, to reduce the impact of LBP and improve quality of life.
摘要：
虽然下腰痛（LBP）可能会持续或随着时间的推移复发，很少有研究长期评估LBP的个体病程，尤其是在老年人中。根据男性纵向骨质疏松性骨折（MrOS）研究的数据，我们旨在识别和描述老年男性不同的LBP轨迹,并对每个轨迹组的成员进行表征.分析了在美国六个地点注册的5,976名社区居民（平均年龄=74.2）。参与者在最长10年内每4个月自我报告一次LBP（是/否）。进行了潜在类别增长建模，以识别解释LBP数据变化的独特LBP轨迹组。使用单变量和多变量多变量逻辑回归评估基线特征与轨迹组成员关系的关联。选择了五类溶液；无/稀有LBP（n=2442/40.9%），低频稳定LBP(n=1040/17.4%)，低频增加LBP(n=719/12%)，中度频率降低的LBP（n=745/12.5%）和高频稳定的LBP（n=1030/17.2%）。跌倒历史（OR=1.52），LBP病史（OR=6.37），在该老年男性样本中,基线时更高的身体损害(OR=1.51-2.85)和更差的心理功能(OR=1.41-1.62)均与更差的LBP轨迹组相关.这些发现为LBP轨迹恶化或增加以及相关可改变的风险因素的老年男性提供了有针对性的干预和/或管理的机会。减少LBP的影响，提高生活质量。
