PDF(Pubmed)
Abstract：
Negative pressure wound therapy is currently one of the most popular treatment approaches that provide a series of benefits to facilitate healing, including increased local blood perfusion with reduced localized oedema and control of wound exudate. The porous foam dressing is a critical element in the application of this therapy and its choice is based on its ability to manage exudate. Industry standards often employ aqueous solutions devoid of proteins to assess dressing performance. However, such standardized tests fail to capture the intricate dynamics of real wounds, oversimplifying the evaluation process. This study aims to evaluate the technical characteristics of two different commercial polyurethane foam dressings during negative pressure wound therapy. We introduce an innovative experimental model designed to evaluate the effects of this therapy on foam dressings in the presence of viscous exudates. Our findings reveal a proportional increase in dressing fibre occupancy as pressure intensifies, leading to a reduction in dressing pore size. The tests underscore the pressure system\'s diminished efficacy in fluid extraction with increasing fluid viscosity. Our discussion points to the need of establishing standardized guidelines for foam dressing selection based on pore size and the necessity of incorporating real biological exudates into industrial standards.
摘要：
负压伤口疗法是目前最流行的治疗方法之一，它提供了一系列促进愈合的益处，包括局部血液灌注增加，局部水肿减少和伤口渗出物控制。多孔泡沫敷料是该疗法应用中的关键因素,并且其选择基于其管理渗出物的能力。工业标准通常采用不含蛋白质的水溶液来评估敷料性能。然而,这种标准化测试无法捕捉到真实伤口的复杂动态，过度简化评估过程。这项研究旨在评估两种不同的商业聚氨酯泡沫敷料在负压伤口治疗期间的技术特征。我们介绍了一种创新的实验模型，旨在评估这种疗法在粘稠渗出物存在下对泡沫敷料的影响。我们的发现表明，随着压力的增强，敷料纤维的占有率成比例地增加，导致敷料孔径减小。测试强调了随着流体粘度的增加，压力系统在流体提取中的功效降低。我们的讨论指出，需要建立基于孔径的泡沫敷料选择的标准化指南，以及将真正的生物渗出物纳入工业标准的必要性。
