PDF(Pubmed)
Abstract：
Cancer constitutes a multifaceted ailment characterized by the dysregulation of numerous genes and pathways. Among these, LIM domain only 7 (LMO7) has emerged as a significant player in various cancer types, garnering substantial attention for its involvement in tumorigenesis and cancer progression. This review endeavors to furnish a comprehensive discourse on the functional intricacies and mechanisms of LMO7 in cancer, with a particular emphasis on its potential as both a therapeutic target and prognostic indicator. It delves into the molecular attributes of LMO7, its implications in cancer etiology and the underlying mechanisms propelling its oncogenic properties. Furthermore, it underscores the extant challenges and forthcoming prospects in targeting LMO7 for combating cancer.
摘要：
癌症构成多方面的疾病,其特征在于许多基因和途径的失调。其中,仅LIM域7（LMO7）已成为各种癌症类型的重要参与者，因其参与肿瘤发生和癌症进展而受到广泛关注。这篇综述努力提供关于LMO7在癌症中的功能复杂性和机制的全面论述。特别强调其作为治疗靶标和预后指标的潜力。它深入研究了LMO7的分子属性，其在癌症病因中的意义以及推动其致癌特性的潜在机制。此外，它强调了针对LMO7对抗癌症的现存挑战和未来前景.
