PDF(Pubmed)
Abstract：
UNASSIGNED: Providing the human papillomavirus (HPV) vaccine is effective to eliminate the disparity in HPV-related cancers. It is unknown regarding inequality in the distribution of HPV vaccination in China since the vaccine was licensed and approved for use in 2016. This study aimed to examine socioeconomic inequalities in HPV-related knowledge and vaccination and identified factors associated with such inequalities.
UNASSIGNED: Self-administered questionnaires measuring HPV-related knowledge and vaccine uptake were completed by 1,306 women through online survey platform. HPV knowledge was assessed using a 12-item question stem that covered the hazards of HPV infection, HPV vaccine dosage, benefits, and protection. Cluster analysis by combining monthly household income, educational level, and employment status was used to identify socioeconomic status (SES) class. The concentration index (CI) was employed as a measure of socioeconomic inequalities in HPV-related knowledge and vaccination. Linear regression and logistic regression were established to decompose the contributions of associated factors to the observed inequalities.
UNASSIGNED: The CI for HPV-related knowledge and vaccine uptake was 0.0442 and 0.1485, respectively, indicating the higher knowledge and vaccination rate were concentrated in groups with high SES. Education and household income made the largest contribution to these inequalities. Age, residency and cervical cancer screening were also important contributors of observed inequalities.
UNASSIGNED: Socioeconomic inequalities in HPV-related knowledge and vaccination uptake are evident in China. Interventions to diffuse HPV-related information for disadvantaged groups are helpful to reduce these inequalities. Providing low or no-cost HPV vaccination and ensuring accessibility of vaccines in rural areas are also considered to be beneficial.
UNASSIGNED: Self-administered questionnaires measuring HPV-related knowledge and vaccine uptake were completed by 1,306 women through online survey platform. HPV knowledge was assessed using a 12-item question stem that covered the hazards of HPV infection, HPV vaccine dosage, benefits, and protection. Cluster analysis by combining monthly household income, educational level, and employment status was used to identify socioeconomic status (SES) class. The concentration index (CI) was employed as a measure of socioeconomic inequalities in HPV-related knowledge and vaccination. Linear regression and logistic regression were established to decompose the contributions of associated factors to the observed inequalities.
UNASSIGNED: The CI for HPV-related knowledge and vaccine uptake was 0.0442 and 0.1485, respectively, indicating the higher knowledge and vaccination rate were concentrated in groups with high SES. Education and household income made the largest contribution to these inequalities. Age, residency and cervical cancer screening were also important contributors of observed inequalities.
UNASSIGNED: Socioeconomic inequalities in HPV-related knowledge and vaccination uptake are evident in China. Interventions to diffuse HPV-related information for disadvantaged groups are helpful to reduce these inequalities. Providing low or no-cost HPV vaccination and ensuring accessibility of vaccines in rural areas are also considered to be beneficial.
摘要：
■提供人乳头瘤病毒（HPV）疫苗可有效消除HPV相关癌症的差异。自2016年该疫苗获得许可并批准使用以来，中国HPV疫苗的分布不平等尚不清楚。这项研究旨在检查与HPV相关的知识和疫苗接种方面的社会经济不平等，并确定与这种不平等相关的因素。
■1,306名妇女通过在线调查平台完成了测量HPV相关知识和疫苗摄取的自我管理问卷。使用涵盖HPV感染危害的12项问题干评估HPV知识，HPV疫苗剂量，好处,和保护。通过结合家庭月收入进行聚类分析，教育水平,就业状况被用来识别社会经济地位(SES)类别。浓度指数（CI）被用作衡量HPV相关知识和疫苗接种中社会经济不平等的指标。建立线性回归和逻辑回归来分解相关因素对观察到的不等式的贡献。
■HPV相关知识和疫苗摄取的TheCI分别为0.0442和0.1485，表明较高的知识和疫苗接种率集中在SES高的人群中。教育和家庭收入对这些不平等的贡献最大。年龄,住院医师和宫颈癌筛查也是观察到的不平等的重要因素.
■在HPV相关知识和疫苗接种方面的社会经济不平等在中国很明显。对弱势群体传播HPV相关信息的干预有助于减少这些不平等。提供低成本或免费的HPV疫苗接种并确保在农村地区获得疫苗也被认为是有益的。
■1,306名妇女通过在线调查平台完成了测量HPV相关知识和疫苗摄取的自我管理问卷。使用涵盖HPV感染危害的12项问题干评估HPV知识，HPV疫苗剂量，好处,和保护。通过结合家庭月收入进行聚类分析，教育水平,就业状况被用来识别社会经济地位(SES)类别。浓度指数（CI）被用作衡量HPV相关知识和疫苗接种中社会经济不平等的指标。建立线性回归和逻辑回归来分解相关因素对观察到的不等式的贡献。
■HPV相关知识和疫苗摄取的TheCI分别为0.0442和0.1485，表明较高的知识和疫苗接种率集中在SES高的人群中。教育和家庭收入对这些不平等的贡献最大。年龄,住院医师和宫颈癌筛查也是观察到的不平等的重要因素.
■在HPV相关知识和疫苗接种方面的社会经济不平等在中国很明显。对弱势群体传播HPV相关信息的干预有助于减少这些不平等。提供低成本或免费的HPV疫苗接种并确保在农村地区获得疫苗也被认为是有益的。
