Abstract：
UNASSIGNED: This study aimed to evaluate the agreement of disease status collected through a survey of the Korean Atomic Bomb Survivor Cohort (K-ABC), compared with medical claim records from the Korean National Health Insurance Service (NHIS) database and the Korean Central Cancer Registry (KCCR).
UNASSIGNED: Data on the lifetime physician-diagnosed morbidities of 1,215 K-ABC participants were collected through an interviewer-administered questionnaire between 2020 and 2022. Survey data were linked to the NHIS and KCCR databases. Eleven diseases were included for validation. We evaluated the following indicators: sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy, the area under the curve (AUC), and the kappa coefficient.
UNASSIGNED: The mean (standard deviation) age was 62.1 (18.7) years, and 42.6% of the participants were aged ≥70 years. Hypertension and cataracts showed the highest prevalence rates (33.8% and 28.8%, respectively). Hypertension, diabetes, and cancer demonstrated high sensitivity (>0.8) and specificity (>0.9), whereas diabetes, cancer, myocardial infarction, angina pectoris, and asthma exhibited high accuracy (>0.9). In contrast, arthritis, allergic rhinitis, and asthma showed low sensitivity (<0.4) and kappa values (<0.3). In the participants aged ≥70 years, the kappa value was ≥0.4 for all diseases except arthritis, allergic rhinitis, and asthma.
UNASSIGNED: The results from this initial analysis showed relatively high agreement between the survey and NHIS/KCCR databases, especially for hypertension, diabetes, and cancer. Our findings suggest that the information on morbidities collected through the questionnaires in this cohort was valid for both younger and older individuals.
UNASSIGNED: Data on the lifetime physician-diagnosed morbidities of 1,215 K-ABC participants were collected through an interviewer-administered questionnaire between 2020 and 2022. Survey data were linked to the NHIS and KCCR databases. Eleven diseases were included for validation. We evaluated the following indicators: sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy, the area under the curve (AUC), and the kappa coefficient.
UNASSIGNED: The mean (standard deviation) age was 62.1 (18.7) years, and 42.6% of the participants were aged ≥70 years. Hypertension and cataracts showed the highest prevalence rates (33.8% and 28.8%, respectively). Hypertension, diabetes, and cancer demonstrated high sensitivity (>0.8) and specificity (>0.9), whereas diabetes, cancer, myocardial infarction, angina pectoris, and asthma exhibited high accuracy (>0.9). In contrast, arthritis, allergic rhinitis, and asthma showed low sensitivity (<0.4) and kappa values (<0.3). In the participants aged ≥70 years, the kappa value was ≥0.4 for all diseases except arthritis, allergic rhinitis, and asthma.
UNASSIGNED: The results from this initial analysis showed relatively high agreement between the survey and NHIS/KCCR databases, especially for hypertension, diabetes, and cancer. Our findings suggest that the information on morbidities collected through the questionnaires in this cohort was valid for both younger and older individuals.
摘要：
■这项研究旨在评估通过对韩国原子弹幸存者队列（K-ABC）的调查收集的疾病状态的一致性，与韩国国家健康保险服务(NHIS)数据库和韩国中央癌症登记处(KCCR)的医疗索赔记录进行比较。
■在2020年至2022年之间，通过面试官管理的问卷收集了1,215名K-ABC参与者的终生医生诊断的发病率数据。调查数据与NHIS和KCCR数据库相关联。包括11种疾病用于验证。我们评估了以下指标：灵敏度，特异性，阳性预测值(PPV)，负预测值(NPV)，准确度,曲线下面积（AUC），和卡帕系数。
■平均（标准差）年龄为62.1（18.7）岁，42.6%的参与者年龄≥70岁.高血压和白内障患病率最高(33.8%和28.8%,分别)。高血压,糖尿病,和癌症表现出高灵敏度（>0.8）和特异性（>0.9），而糖尿病,癌症,心肌梗塞,心绞痛,和哮喘表现出很高的准确性（>0.9）。相比之下,关节炎,过敏性鼻炎,和哮喘显示低敏感性（<0.4）和kappa值（<0.3）。在年龄≥70岁的参与者中，除关节炎外，所有疾病的kappa值≥0.4，过敏性鼻炎,和哮喘。
■此初步分析的结果表明，调查与NHIS/KCCR数据库之间的一致性相对较高，尤其是高血压，糖尿病,和癌症。我们的发现表明，通过该队列中的问卷收集的有关发病率的信息对年轻人和老年人均有效。
■在2020年至2022年之间，通过面试官管理的问卷收集了1,215名K-ABC参与者的终生医生诊断的发病率数据。调查数据与NHIS和KCCR数据库相关联。包括11种疾病用于验证。我们评估了以下指标：灵敏度，特异性，阳性预测值(PPV)，负预测值(NPV)，准确度,曲线下面积（AUC），和卡帕系数。
■平均（标准差）年龄为62.1（18.7）岁，42.6%的参与者年龄≥70岁.高血压和白内障患病率最高(33.8%和28.8%,分别)。高血压,糖尿病,和癌症表现出高灵敏度（>0.8）和特异性（>0.9），而糖尿病,癌症,心肌梗塞,心绞痛,和哮喘表现出很高的准确性（>0.9）。相比之下,关节炎,过敏性鼻炎,和哮喘显示低敏感性（<0.4）和kappa值（<0.3）。在年龄≥70岁的参与者中，除关节炎外，所有疾病的kappa值≥0.4，过敏性鼻炎,和哮喘。
■此初步分析的结果表明，调查与NHIS/KCCR数据库之间的一致性相对较高，尤其是高血压，糖尿病,和癌症。我们的发现表明，通过该队列中的问卷收集的有关发病率的信息对年轻人和老年人均有效。
