PDF(Pubmed)
Abstract：
The objective of this umbrella review was to investigate comprehensive and synthesized evidence of the association between ambient air pollution and obesity based on the current systematic reviews and meta-analyses. Related studies from databases including PubMed, EMBASE, Web of Science, and the Cochrane Library, published before July 16, 2023, were considered in the analysis. All selected systematic reviews and meta-analyses were included in accordance with PRISMA guidelines. The risk of bias and the methodological quality were evaluated using the AMSTAR 2 tool. The protocol for this umbrella review was documented in PROSPERO with the registration number: CRD42023450191. This umbrella review identified 7 studies, including 5 meta-analyses and 2 systematic reviews, to assess the impacts of air pollutants on obesity. Commonly examined air pollutants included PM1, PM2.5, PM10, NO2, SO2, O3. Most of the included studies presented that air pollution exposure was positively associated with the increased risk of obesity. The impact of air pollution on obesity varied by different ambient air pollutants. This study provided compelling evidence that exposure to air pollution had a positive association with the risk of obesity. These findings further indicate the importance of strengthening air pollution prevention and control. Future studies should elucidate the possible mechanisms and pathways linking air pollution to obesity.
摘要：
本综述的目的是基于当前的系统评价和荟萃分析，调查环境空气污染与肥胖之间关联的综合和综合证据。来自包括PubMed在内的数据库的相关研究，EMBASE,WebofScience,还有Cochrane图书馆,在分析中考虑了2023年7月16日之前发布的。所有选定的系统评价和荟萃分析均按照PRISMA指南纳入。使用AMSTAR2工具评估偏倚风险和方法学质量。该总括审查的方案记录在PROSPERO中，注册号为：CRD42023450191。这项综述确定了7项研究，包括5个荟萃分析和2个系统综述，评估空气污染物对肥胖的影响。通常检查的空气污染物包括PM1，PM2.5，PM10，NO2，SO2，O3。大多数纳入的研究表明，空气污染暴露与肥胖风险增加呈正相关。空气污染对肥胖的影响因不同的环境空气污染物而异。这项研究提供了令人信服的证据，表明暴露于空气污染与肥胖风险呈正相关。这些发现进一步表明了加强大气污染防治的重要性。未来的研究应该阐明将空气污染与肥胖联系起来的可能机制和途径。
