关键词: Cataract Diabetic macular edema Ozurdex Vitrectomy

Mesh : Humans Dexamethasone / administration & dosage Male Aged, 80 and over Glucocorticoids / administration & dosage Drug Implants / adverse effects Lens, Crystalline / surgery Macular Edema / drug therapy etiology diagnosis Phacoemulsification Lens Implantation, Intraocular / adverse effects Visual Acuity Intravitreal Injections

来  源:   DOI:10.1186/s12886-024-03538-y   PDF(Pubmed)

Abstract:
BACKGROUND: To report a case of cataract surgery in unintentional Ozurdex (Allergan, Inc., Irvine, California, USA) injection into the lens.
METHODS: A 82-years old man reporting decreased visual acuity in his right eye came to our Ophthalmology service. Due to the clinical history, and on the basis of ophthalmoscopic and imaging examinations diabetic macular edema was diagnosed. Thus, intravitreal dexamethasone implant was scheduled and therefore performed. The following day Ozurdex appeared to be located into the lens. After careful evaluation and strict follow up examinations, due to the risks associated with the presence of the implant into the lens, phacoemulsification with Ozurdex removal and intraocular lens (IOL) implantation was scheduled and performed.
CONCLUSIONS: In this case report we reported the surgical management of accidental into-the lens dexamethasone implant carefully taking into account the dexamethasone pharmacokinetic.
摘要:
背景:报告一例无意的Ozurdex白内障手术(Allergan,Inc.,Irvine,加州,美国)注入透镜。
方法:一位82岁的男性报告他的右眼视力下降来到我们的眼科服务。由于临床病史,并根据眼底镜和影像学检查诊断为糖尿病性黄斑水肿。因此,安排并因此进行玻璃体内地塞米松植入。第二天,Ozurdex似乎位于镜头中。经过认真评估和严格的后续检查,由于与植入晶状体相关的风险,安排并进行了超声乳化摘除Ozurdex和人工晶状体(IOL)植入。
结论:在本病例报告中,我们报告了仔细考虑地塞米松药代动力学的意外植入晶状体的手术处理。
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