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Abstract：
The study aimed to evaluate the prevalence, risk factors, and clinical outcomes of pulmonary embolism in patients diagnosed with sepsis with and without shock. The National Inpatient Sample was used to identify adults with sepsis with and without shock between 2017 and 2019. The prevalence of acute pulmonary embolism and the association of acute pulmonary embolism with in-hospital mortality, hospital length of stay for survivors, and overall costs of hospitalization were evaluated. Multivariable logistic and linear regression analyses, adjusted for various parameters, were used to explore these associations. Of the estimated 5,019,369 sepsis hospitalizations, 1.2% of patients with sepsis without shock and 2.3% of patients with septic shock developed pulmonary embolism. The odds ratio for in-hospital mortality was 1.94 (95% confidence interval (CI) 1.85-2.03, p < 0.001). The coefficient for hospital length of stay was 3.24 (95% CI 3.03-3.45, p < 0.001). The coefficient for total costs was 46,513 (95% CI 43,079-49,947, p < 0.001). The prevalence of pulmonary embolism in patients diagnosed with sepsis with and without shock was 1.2 and 2.3%, respectively. Acute pulmonary embolism was associated with higher in-hospital mortality, longer hospital length of stay for survivors, and higher overall costs of hospitalization.
摘要：
这项研究旨在评估患病率，危险因素，以及诊断为脓毒症伴和不伴休克患者的肺栓塞的临床结局。国家住院患者样本用于识别2017年至2019年间有和没有休克的脓毒症成年人。急性肺栓塞的患病率以及急性肺栓塞与院内死亡率的关系，幸存者住院时间,并对住院总费用进行了评估.多变量逻辑和线性回归分析，针对各种参数进行了调整，被用来探索这些关联。在估计的5,019,369例败血症住院中，1.2%无休克的脓毒症患者和2.3%的脓毒性休克患者发生肺栓塞。住院死亡率的比值比为1.94（95％置信区间（CI）1.85-2.03，p<0.001）。住院时间系数为3.24（95％CI3.03-3.45，p<0.001）。总成本系数为46,513（95%CI43,079-49,947，p<0.001）。诊断为脓毒症伴休克和不伴休克患者的肺栓塞患病率分别为1.2％和2.3％，分别。急性肺栓塞与更高的院内死亡率相关,幸存者住院时间更长，以及更高的住院总费用。
