Abstract:
The widespread use of antibiotics often increases bacterial resistance. Herein, we reported a silver peroxide-incorporated carbon dots (defined as Ag2O2-CDs) with high photothermal conversion efficiency viain situoxidation process. The prepared Ag2O2-CDs exhibited ultra-small size of 2.0 nm and hybrid phase structure. Meanwhile, the Ag2O2-CDs were of a similar optical performance comparing with traditional carbon dots (CDs). Importantly, the incorporation of Ag2O2into CDs significantly enhanced photothermal conversion efficiency from 3.8% to 28.5%. By combining silver ion toxicity and photothermal ablation, the Ag2O2-CDs were capable of destroying gram-positive and gram-negative bacterium effectively. These findings demonstrated that the Ag2O2-CDs could be served as a potential antibacterial agent for clinical applications.
摘要:
抗生素的广泛使用通常导致细菌耐药性增加。在这里,我们报道了通过原位氧化过程具有高光热转化效率的过氧化银掺入的碳点(定义为Ag2O2-CD)。制备的Ag2O2-CD具有2.0nm的超小尺寸和杂化相结构。同时,Ag2O2-CD具有与传统碳点(CD)相似的光学性能。重要的是,将Ag2O2掺入CD中可将光热转换效率从3.8%显着提高到28.5%。通过结合银离子毒性和光热消融,Ag2O2-CD能够有效地破坏革兰氏阳性和革兰氏阴性细菌。这些发现表明,Ag2O2-CD可以作为临床应用的潜在抗菌剂。
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