Abstract：
Although many cross-sectional studies showed that psychotic experiences (PEs) and dissociation were closely related, the longitudinal association between them remains unknown. Therefore, the aim of the current study was to examine the longitudinal association of these two symptoms throughout adolescence, under the hypothesis that these two symptoms are bidirectionally associated. Data were obtained from a population-based cohort, the Tokyo Teen Cohort study (TTC; N = 3171). PEs and dissociation were assessed at 10, 12, 14, and 16 years of age. PEs were assessed using a total score from five-item self-report questionnaires derived from the Diagnostic Interview Schedule for Children (DISC-C). Dissociation was assessed using subscale scores of the Child Behavior Checklist (CBCL) completed by primary caregivers. We examined the longitudinal relationship between PEs and dissociation using the random intercept cross-lagged panel model (RI-CLPM). The within-person component of the RI-CLPM revealed no significant cross-lagged effect of dissociation on PEs at any time point. On the other hand, there was a significant (p < 0.05) association between PEs at age 14 and dissociation at age 16 (β = 0.106, 95 % CI 0.047-0.165). The between-person component revealed a significant time-invariant relationship between the two symptoms (β = 0.324, 95 % CI 0.239-0.410). The longitudinal relationship between PEs and dissociation was limited at the within-person level, whereas the between-person correlation was significant. The only significant longitudinal pathway was from PEs to dissociation, suggesting that PEs may be a predictor of dissociation in mid-adolescence.
摘要：
尽管许多横断面研究表明，精神病经历（PE）和分离密切相关，它们之间的纵向关联仍然未知。因此,当前研究的目的是检查这两种症状在整个青春期的纵向关联，假设这两种症状是双向相关的。数据来自基于人群的队列，东京青少年队列研究（TTC；N=3171）。在10、12、14和16岁时评估PE和解离。PE使用来自儿童诊断性访谈时间表（DISC-C）的五项自我报告问卷的总分进行评估。使用主要护理人员完成的儿童行为清单（CBCL）的子量表评分评估离解。我们使用随机截距交叉滞后面板模型（RI-CLPM）检查了PE与解离之间的纵向关系。RI-CLPM的人内成分在任何时间点都没有发现解离对PE的明显交叉滞后作用。另一方面,14岁时的PE与16岁时的解离之间存在显着关联（p<0.05）（β=0.106，95％CI0.047-0.165）。人与人之间的成分显示出两种症状之间的显着时不变关系（β=0.324，95％CI0.239-0.410）。PE和解离之间的纵向关系在人内水平上受到限制，而人与人之间的相关性是显著的。唯一重要的纵向途径是从PE到解离，这表明PE可能是青春期中期离解的预测因子。
