关键词: N,N-dimethylpentylone New psychoactive substances Prisons Synthetic cathinones

Mesh : Humans Gas Chromatography-Mass Spectrometry Alkaloids / analysis Illicit Drugs / analysis chemistry Prisons Psychotropic Drugs / analysis chemistry Designer Drugs / analysis chemistry Substance Abuse Detection / methods

来  源:   DOI:10.1016/j.forsciint.2024.112145

Abstract:
Drug use is prevalent in prisons with drugs associated with depressant effects found to be more prevalent than stimulants. Synthetic cathinones (SCats; often sold as \"bath salts\", \"ecstasy\", \"molly\", and \"monkey dust\") are the second largest category of new psychoactive substances (NPS) currently monitored by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) and are commonly used as substitutes for regulated stimulants, such as amphetamine, cocaine, and MDMA. N,N-dimethylpentylone (also known as dimethylpentylone, dipentylone, and bk-DMBDP) was detected for the first time in the Scottish prisons in seven powder samples seized between January and July 2023. Samples were analyzed using gas chromatography-mass spectrometry (GC-MS), ultra-high performance liquid chromatography-quadrupole time of flight mass spectrometry (UPLC-QToF-MS), and nuclear magnetic resonance imaging (NMR). Dimethylpentylone was detected alongside other drugs in four samples, including the novel benzodiazepine desalkylgidazepam (bromonordiazepam) and the synthetic cannabinoid receptor agonists (SCRAs) MDMB-INACA and MDMB-4en-PINACA.
摘要:
在监狱中,药物使用很普遍,与抑郁症相关的药物比兴奋剂更普遍。合成卡西酮(SCats;通常以“浴盐”出售,\"摇头丸\",\"Molly\",和\"猴尘\")是目前由欧洲药物和药物成瘾监测中心(EMCDDA)监测的第二大类新精神活性物质(NPS),通常用作受管制兴奋剂的替代品,比如安非他明,可卡因,MDMAN,N-二甲基戊酮(也称为二甲基戊酮,二戊酮,和bk-DMBDP)在2023年1月至7月之间缉获的七个粉末样品中首次在苏格兰监狱中被发现。使用气相色谱-质谱(GC-MS)分析样品,超高效液相色谱-四极杆飞行时间质谱(UPLC-QToF-MS),核磁共振成像(NMR)。在四个样本中与其他药物一起检测到二甲基戊酮,包括新型苯二氮卓去烷基吉达西泮(溴诺地西泮)和合成大麻素受体激动剂(SCRAs)MDMB-INACA和MDMB-4en-PINACA。
公众号